Molecular structure of Nε,Nε,Nε-Trimethyllysine hydrochloride, CAS Number: 55528-53-5
Nε,Nε,Nε-Trimethyllysine hydrochloride (CAS 55528-53-5)
Alternate Names:
Nε-(trimethyl)-L-lysine chloride; H-Nε-(trimethyl)-L-lysine chloride
Application:
Nε,Nε,Nε-Trimethyllysine hydrochloride is a non-protein amino acid active in the biosynthesis of carnitine
CAS Number:
55528-53-5
Purity:
98%
Molecular Weight:
224.73
Molecular Formula:
C9H20N2O2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Nepsilon-trimethyllysine (TML) is a non-protein amino acid which takes part in the biosynthesis of carnitine. In mammals, the breakdown of endogenous proteins containing TML residues is a starting point for carnitine biosynthesis. Nε,Nε,Nε-Trimethyllysine hydrochloride is primarly used in lysine methylation modification assays and purifications.
Nε,Nε,Nε-Trimethyllysine hydrochloride (CAS 55528-53-5) References
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- Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase. | Couture, JF., et al. 2007. Nat Struct Mol Biol. 14: 689-95. PMID: 17589523
- Enzymology of the carnitine biosynthesis pathway. | Strijbis, K., et al. 2010. IUBMB Life. 62: 357-62. PMID: 20306513
- Synthesis of new trisulfonated calix[4]arenes functionalized at the upper rim, and their complexation with the trimethyllysine epigenetic mark. | Daze, KD., et al. 2012. Org Lett. 14: 1512-5. PMID: 22397706
- Binding trimethyllysine and other cationic guests in water with a series of indole-derived hosts: large differences in affinity from subtle changes in structure. | Whiting, AL. and Hof, F. 2012. Org Biomol Chem. 10: 6885-92. PMID: 22828995
- Selective molecular recognition of methylated lysines and arginines by cucurbit[6]uril and cucurbit[7]uril in aqueous solution. | Gamal-Eldin, MA. and Macartney, DH. 2013. Org Biomol Chem. 11: 488-95. PMID: 23202694
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- Unique and Novel Urinary Metabolomic Features in Malignant versus Benign Adrenal Neoplasms. | Patel, D., et al. 2017. Clin Cancer Res. 23: 5302-5310. PMID: 28450405
- Comparative metabolomics revealing Staphylococcus aureus metabolic response to different antibiotics. | Schelli, K., et al. 2017. Microb Biotechnol. 10: 1764-1774. PMID: 28815967
- Identification of methylated tubulin through analysis of methylated lysine. | Suzuki, R., et al. 2018. Anal Bioanal Chem. 410: 4189-4194. PMID: 29732499
- epsilon-N-trimethyllysine availability regulates the rate of carnitine biosynthesis in the growing rat. | Rebouche, CJ., et al. 1986. J Nutr. 116: 751-9. PMID: 3084726
- Biofluid Metabolomics of Mice Exposed to External Low-Dose Rate Radiation in a Novel Irradiation System, the Variable Dose-Rate External 137Cs Irradiator. | Pannkuk, EL., et al. 2021. J Proteome Res. 20: 5145-5155. PMID: 34585931
- Biofluid Metabolomics and Lipidomics of Mice Exposed to External Very High-Dose Rate Radiation. | Pannkuk, EL., et al. 2022. Metabolites. 12: PMID: 35736453
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nε,Nε,Nε-Trimethyllysine hydrochloride, 25 mg | sc-215597 | 25 mg | $288.00 |