NEPH3 Antibody (5E6): sc-81795
- NEPH3 Antibody (5E6) is a mouse monoclonal IgG2a κ provided at 100 µg/ml
- raised against recombinant NEPH3 of human origin
- recommended for detection of NEPH3 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for NEPH3 Antibody (5E6). This work is in progress.
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NEPH3 Antibody (5E6) is a mouse monoclonal IgG2a antibody that detects NEPH3 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). NEPH3, also known as nephrin-like protein 3, NLG1, FILTRIN, or KIRREL2, is a 708 amino acid protein belonging to the immunoglobulin superfamily of cell adhesion molecules. NEPH3 plays a crucial role in maintaining the integrity of the glomerular filtration barrier in the kidney, which is essential for proper kidney function and filtration of blood. NEPH3 is localized to the interpodocyte filtration slit in the kidney and is also found in the Langerhans islet beta cells of the pancreas, where NEPH3 is involved in pancreatic development. NEPH3 presence is vital for preventing proteinuria, a condition characterized by excess protein in the urine, which can indicate kidney damage. Additionally, NEPH3 undergoes post-translational modifications, including glycosylation, which are important for stability and function. Anti-NEPH3 antibody (5E6) is an invaluable tool for researchers studying kidney function, disease mechanisms, and the role of cell adhesion molecules in various biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NEPH3 Antibody (5E6) | sc-81795 | 100 µg/ml | $339.00 |