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Neotetrazolium Chloride (CAS 298-95-3)

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Alternate Names:
2,2′,5,5′-Tetraphenyl-3,3′-[p-diphenylene] ditetrazolium chloride
Application:
Neotetrazolium Chloride is a compound used for the histochemical detection of dehydrogenases
CAS Number:
298-95-3
Purity:
≥90%
Molecular Weight:
667.59
Molecular Formula:
C38H28Cl2N8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Neotetrazolium chloride is use for the histochemical detection of dehydrogenases. It is also used as reagent for spectrophotometric determination of manganese. Neotetrazolium chloride is also used in microbial growth assays. Its applications extend to measuring cellular respiration rates and detecting the presence of enzymes. It is used to assess cell growth, detecting cell death, and identifying apoptosis.


Neotetrazolium Chloride (CAS 298-95-3) References

  1. Effect of cocaine on mitochondrial electron transport chain evaluated in primary cultures of neonatal rat myocardial cells and in isolated mitochondrial preparations.  |  Yuan, C. and Acosta, D. 2000. Drug Chem Toxicol. 23: 339-48. PMID: 10826100
  2. The use of neotetrazolium chloride in cultures of tubercle bacilli.  |  WINTERSCHEID, LC., et al. 1953. Am Rev Tuberc. 68: 625-8. PMID: 13104876
  3. The radiomimetic effect of neotetrazolium chloride on the skin of mice.  |  ARGYRIS, TS. 1957. Anat Rec. 127: 697-709. PMID: 13458819
  4. Investigation of the extraction equilibria in the system hexachloridorhenate(IV)-neotetrazolium chloride-dichloroethane-water.  |  Simeonova, Z., et al. 1995. Talanta. 42: 867-9. PMID: 18966303
  5. Neotetrazolium chloride: a new reagent for spectrophotometric determination of manganese.  |  Kamburova, M. 1998. Talanta. 46: 1073-8. PMID: 18967231
  6. Vibriocidal assays to determine the antibody titer of patient sera samples.  |  Son, MS. and Taylor, RK. 2011. Curr Protoc Microbiol. Chapter 6: Unit6A.3. PMID: 22045586
  7. Ion-association complexes of gallium(III)-4-(2-pyridylazo)-resorcinol anionic chelates and dicationic tetrazolium reagents.  |  Stojnova, KT., et al. 2013. Acta Chim Slov. 60: 390-6. PMID: 23878944
  8. Evaluation of Inhibitors for Rapid Enumeration of Psychrotrophic Bacteria.  |  Smith, TL. and Witter, LD. 1979. J Food Prot. 42: 158-160. PMID: 30812334
  9. [A new sensitivity test for substances used as antiseptics or disinfectants. I. Biological studies].  |  Dodin, A., et al. 1988. Bull Soc Pathol Exot Filiales. 81: 726-31. PMID: 3146445
  10. A modified tetrazolium reaction for identifying malignant cells from gastric and colonic cancer.  |  Ibrahim, KS., et al. 1983. J Clin Pathol. 36: 133-6. PMID: 6186695
  11. A quantitative cytochemical method for the measurement of beta-hydroxyacyl CoA dehydrogenase activity in rat heart muscle.  |  Chambers, DJ., et al. 1982. Histochemistry. 75: 67-76. PMID: 7118583
  12. The use of tetrazolium salts to determine sites of damage to the mitochondrial electron transport chain in intact cells following in vitro photodynamic therapy with Photofrin II.  |  Musser, DA. and Oseroff, AR. 1994. Photochem Photobiol. 59: 621-6. PMID: 8066121

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Neotetrazolium Chloride, 1 g

sc-295914
1 g
$44.00

Neotetrazolium Chloride, 5 g

sc-295914A
5 g
$185.00

Neotetrazolium Chloride, 25 g

sc-295914B
25 g
$815.00