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Neospiramycin (CAS 70253-62-2)

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Alternate Names:
Neo Spiramycin I
Application:
Neospiramycin is a major metabolite of Spiramycin I in meat, fish, and milk
CAS Number:
70253-62-2
Molecular Weight:
698.88
Molecular Formula:
C36H62N2O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Neospiramycin is a major metabolite of Spiramycin I in meat, fish, and milk. Neospiramycin, a broad-spectrum antibiotic, demonstrates efficacy against both Gram-positive and Gram-negative bacteria. It finds relevance in scientific research endeavors encompassing antibiotic resistance, the advancement of novel antibiotics, and investigations into bacterial physiology and metabolism. Neospiramycin serves as a tool in expanding our understanding of bacterial mechanisms and therapeutic approaches.


Neospiramycin (CAS 70253-62-2) References

  1. Treatment of toxoplasmosis in pregnancy: concentrations of spiramycin and neospiramycin in maternal serum and amniotic fluid.  |  Gratzl, R., et al. 2002. Eur J Clin Microbiol Infect Dis. 21: 12-6. PMID: 11913495
  2. Acid catalysed degradation of some spiramycin derivatives found in the antibiotic bitespiramycin.  |  Shi, X., et al. 2004. J Pharm Biomed Anal. 36: 593-600. PMID: 15522535
  3. Simultaneous multiresidue determination of metronidazole and spiramycin in fish muscle using high performance liquid chromatography with UV detection.  |  Maher, HM., et al. 2008. J Chromatogr B Analyt Technol Biomed Life Sci. 876: 175-81. PMID: 19013111
  4. Determination of spiramycin and neospiramycin antibiotic residues in raw milk using LC/ESI-MS/MS and solid-phase extraction.  |  Wang, J. and Leung, D. 2009. J Sep Sci. 32: 681-8. PMID: 19165836
  5. Fate of antibacterial spiramycin in river waters.  |  Calza, P., et al. 2010. Anal Bioanal Chem. 396: 1539-50. PMID: 19960340
  6. Evaluation of residual antibacterial potency in antibiotic production wastewater using a real-time quantitative method.  |  Zhang, H., et al. 2015. Environ Sci Process Impacts. 17: 1923-9. PMID: 26395288
  7. Simultaneous determination of 16 macrolide antibiotics and 4 metabolites in milk by using Quick, Easy, Cheap, Effective, Rugged, and Safe extraction (QuEChERS) and high performance liquid chromatography tandem mass spectrometry.  |  Zhou, W., et al. 2017. J Chromatogr B Analyt Technol Biomed Life Sci. 1061-1062: 411-420. PMID: 28806686
  8. Multiplex immunoassay based on biochip technology for the screening of antibiotic residues in milk: validation according to the European guideline.  |  Gaudin, V., et al. 2018. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 35: 2348-2365. PMID: 30513250
  9. Veterinary pharmaceutical residues in water resources and tap water in an intensive husbandry area in France.  |  Charuaud, L., et al. 2019. Sci Total Environ. 664: 605-615. PMID: 30763841
  10. A liquid chromatography coupled to tandem mass spectrometry method for the quantification of spiramycin and its active metabolite neospiramycin in milk of major and minor species: Validation using the accuracy profile.  |  Tardiveau, J., et al. 2021. J Chromatogr B Analyt Technol Biomed Life Sci. 1187: 123013. PMID: 34808577
  11. Determination of spiramycin and neospiramycin in plasma and milk of lactating cows by reversed-phase high-performance liquid chromatography.  |  Renard, L., et al. 1994. J Chromatogr B Biomed Appl. 657: 219-26. PMID: 7952072
  12. Confirmatory analysis for spiramycin residue in bovine muscle by liquid chromatography/particle beam mass spectrometry.  |  Sanders, P. and Delépine, B. 1994. Biol Mass Spectrom. 23: 369-75. PMID: 8038231
  13. Study of the metabolism of spiramycin in pig liver.  |  Mourier, P. and Brun, A. 1997. J Chromatogr B Biomed Sci Appl. 704: 197-205. PMID: 9518151

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Neospiramycin, 10 mg

sc-391947
10 mg
$377.00

Neospiramycin, 100 mg

sc-391947A
100 mg
$2193.00