Neoaureothin CAS: 28900-27-8
MF: C28H31NO6
MW: 477.55
A chain-extended analog of aureothin.

Neoaureothin (CAS 28900-27-8)

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Alternate Names: Spectabilin
Application: Neoaureothin is a chain-extended analog of aureothin
CAS Number: 28900-27-8
Purity: ≥98%
Molecular Weight: 477.55
Molecular Formula: C28H31NO6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Neoaureothin is an unusual chain-extended analogue of aureothin. It was first reported as a co-metabolite ofneoantimycin in Streptomyces orinoci. It has been reported to have anti-HIV and antifungal activity. Possesses potent nematocidal and antitumor activity. Two photo-isomers of neoaureothin, Antibiotics SNF4435C and D, have been identified as potent immunosuppressive agents.


References

1. New antibiotics produced by Streptoverticillium orinoci, n. sp. Cassinelli G. et al. Arch. Mikrobiol. 1967, 55, 358.

Physical State :
Solid
Derived From :
Streptomyces sp.
Solubility :
Soluble in DMSO, DMF, water (poor), ethanol, and methanol.
Storage :
Store at -20° C
Melting Point :
252.86° C (Predicted)
Boiling Point :
660.71° C at 760 mmHg (Predicted)
Density :
1.20 g/cm3 (Predicted)
Refractive Index :
n20D 1.59 (Predicted)
IC50 :
NADH fumarate reductase: IC50 = 15 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
6382650
MDL Number :
MFCD11111614
SMILES :
CC1=C(OC(=C(C1=O)C)OC)C2CC(=CC(=CC(=CC(=CC3=CC=C(C=C3)[N+](=O)[O-])C)C)C)CO2

Download SDS (MSDS)

Certificate of Analysis

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