Neoaureothin is an unusual chain-extended analogue of aureothin. It was first reported as a co-metabolite ofneoantimycin in Streptomyces orinoci. It has been reported to have anti-HIV and antifungal activity. Possesses potent nematocidal and antitumor activity. Two photo-isomers of neoaureothin, Antibiotics SNF4435C and D, have been identified as potent immunosuppressive agents.
1. New antibiotics produced by Streptoverticillium orinoci, n. sp. Cassinelli G. et al. Arch. Mikrobiol. 1967, 55, 358.
Soluble in DMSO, DMF, water (poor), ethanol, and methanol.
Store at -20° C
252.86° C (Predicted)
660.71° C at 760 mmHg (Predicted)
1.20 g/cm3 (Predicted)
n20D 1.59 (Predicted)
NADH fumarate reductase: IC50 = 15 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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