NDUFA4 Antibody (2G7): sc-517091

NDUFA4 Antibody (2G7) is a mouse monoclonal IgG1 antibody that detects NDUFA4 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-NDUFA4 antibody (2G7) is available as a non-conjugated format. NDUFA4, also known as NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4 or MLRQ, is an 81 amino acid protein localized to the matrix side of the inner mitochondrial membrane and belongs to the complex I NDUFA4 subunit family. NDUFA4 functions as an accessory component of the multi-protein membrane respiratory chain NADH dehydrogenase complex (Complex I), facilitating electron transfer from NADH to the respiratory chain - a process essential for ATP production and cellular energy metabolism. Proper functioning of NDUFA4 is vital, as disruptions in NDUFA4 activity can lead to impaired mitochondrial function and contribute to various metabolic disorders. NDUFA4 monoclonal antibody (2G7) serves as an invaluable tool for researchers studying mitochondrial function and related pathologies, providing insights into the intricate mechanisms of cellular energy production.

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NDUFA4 Antibody (2G7) References:

1. Novel localization of OCTN1, an organic cation/carnitine transporter, to mammalian mitochondria.  |  Lamhonwah, AM. and Tein, I. 2006. Biochem Biophys Res Commun. 345: 1315-25. PMID: 16729965
2. Adaptive selection of mitochondrial complex I subunits during primate radiation.  |  Mishmar, D., et al. 2006. Gene. 378: 11-8. PMID: 16828987
3. Cloning of the human cDNA sequence encoding the NADH:ubiquinone oxidoreductase MLRQ subunit.  |  Kim, JW., et al. 1997. Biochem Mol Biol Int. 43: 669-75. PMID: 9352085
4. cDNA of eight nuclear encoded subunits of NADH:ubiquinone oxidoreductase: human complex I cDNA characterization completed.  |  Loeffen, JL., et al. 1998. Biochem Biophys Res Commun. 253: 415-22. PMID: 9878551

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-NDUFA4 Antibody (2G7) has 3 citations in a variety of scientific publications.

Primary antibodies like Anti-NDUFA4 Antibody (2G7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

NDUFA4 Antibody (2G7) Specifications

Alternate Product Name: NDUFA4

Product Clone Name: 2G7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ lambda light chain

Amino Acids: 1-81

Epitope Target: NDUFA4

Epitope Species: human

Product Reactivity/Detection: NDUFA4

Species Reactivity/Detection: human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, ELISA

Vialing Information: Each vial contains 100 µg IgG₁ lambda light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 3 citations in various scientific publications

Available Conjugates/Forms for NDUFA4 Antibody (2G7): N/A