NDST3 Antibody (JK-3): sc-100789

NDST3 Antibody (JK-3) is a mouse monoclonal IgG2a antibody that detects NDST3 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). NDST3, a member of the N-deacetylase/N-sulfotransferase family, plays a crucial role in the modification of heparan sulfate and heparin, which are essential for various biological processes, including cell signaling, growth factor activity, and the regulation of cell adhesion. The proper functioning of NDST3 is vital as NDST3 catalyzes the N-deacetylation and N-sulfation of N-acetylglucosamine residues, leading to the generation of oligosaccharide sequences with specific ligand-binding properties. This enzymatic activity is critical for the synthesis of heparan sulfate proteoglycans, which are involved in numerous physiological processes, including embryonic development and tissue repair. The expression of NDST3 is tightly regulated and is often linked to specific tissue types, highlighting NDST3′s importance in maintaining cellular functions and interactions. Anti-NDST3 antibody (JK-3) is an invaluable tool for researchers aiming to explore the intricate roles of NDST3 in human health and disease.