NDSB-221 (CAS 160788-56-7)
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NDSB-221, scientifically known as N-dodecyl-N,N-dimethyl-2-ammonioethyl sulfate, serves as a crucial tool in various research applications, particularly in biochemistry and molecular biology. Its mechanism of action stems from its amphiphilic nature, allowing it to solubilize and stabilize membrane proteins by disrupting hydrophobic interactions. This property is especially valuable in studies involving integral membrane proteins, where maintaining protein integrity in aqueous solutions is challenging. NDSB-221 has been extensively used in membrane protein research, facilitating the extraction, purification, and characterization of membrane-bound proteins. Its ability to stabilize membrane proteins in their native conformation has enabled structural and functional studies using techniques such as X-ray crystallography, cryo-electron microscopy, and spectroscopic methods. Furthermore, NDSB-221 has found applications in the development of protein-based biosensors, drug discovery, and understanding cellular signaling pathways involving membrane proteins. Its versatility and effectiveness in membrane protein research make it a valuable tool for scientists exploring the structure, function, and interactions of membrane proteins, with implications in various fields, including biotechnology, pharmacology, and structural biology.
NDSB-221 (CAS 160788-56-7) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NDSB-221, 5 g | sc-222051 | 5 g | $118.00 | |||
NDSB-221, 25 g | sc-222051A | 25 g | $403.00 |