Naringenin 7-O-β-D-Glucuronide Sodium Salt (Mixture of Diastereomers) (CAS 158196-34-0 non-salt)

Naringenin 7-O-β-D-glucuronide (mixture of diastereomers) is a modified form of naringenin, a flavonoid compound, which has been conjugated with glucuronic acid to form a glucuronide. This modification typically occurs as part of the body′s natural process to enhance the solubility and excretion of hydrophobic molecules. In research, this compound is of interest for studying phase II metabolism, particularly glucuronidation, a key detoxification pathway for a variety of xenobiotics and endogenous substances. The mixture of diastereomers provides a model for understanding the stereospecificity and enzyme-substrate interactions of the enzymes involved in glucuronidation, such as the UDP-glucuronosyltransferases. Additionally, Naringenin 7-O-β-D-glucuronide is used in analytical studies to develop and validate methods for detecting and quantifying flavonoid glucuronides in biological samples, such as blood or urine. This work is essential for elucidating the kinetic profiles of flavonoid compounds and their metabolites.