Molecular structure of Naratriptan Hydrochloride, CAS Number: 143388-64-1
Naratriptan Hydrochloride (CAS 143388-64-1)
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Alternate Names:
N-Methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]ethanesulfonamide Hydrochloride
Application:
Naratriptan Hydrochloride is an agonist of SR-1.
CAS Number:
143388-64-1
Molecular Weight:
371.93
Molecular Formula:
C17H25N3O2S•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Naratriptan Hydrochloride is a triptan drug which is used for the treatment of migraine headaches.
Naratriptan Hydrochloride (CAS 143388-64-1) References
- Characterisation of the 5-HT receptor binding profile of eletriptan and kinetics of [3H]eletriptan binding at human 5-HT1B and 5-HT1D receptors. | Napier, C., et al. 1999. Eur J Pharmacol. 368: 259-68. PMID: 10193663
- Determination of antimigraine compounds rizatriptan, zolmitriptan, naratriptan and sumatriptan in human serum by liquid chromatography/electrospray tandem mass spectrometry. | Vishwanathan, K., et al. 2000. Rapid Commun Mass Spectrom. 14: 168-72. PMID: 10637423
- Naratriptan has a selective inhibitory effect on trigeminovascular neurones at central 5-HT1A and 5-HT(1B/1D) receptors in the cat: implications for migraine therapy. | Boers, PM., et al. 2004. Cephalalgia. 24: 99-109. PMID: 14728705
- Reinforced spatial alternation as an animal model of obsessive-compulsive disorder (OCD): investigation of 5-HT2C and 5-HT1D receptor involvement in OCD pathophysiology. | Tsaltas, E., et al. 2005. Biol Psychiatry. 57: 1176-85. PMID: 15866558
- Quantitative analysis of eletriptan in human plasma by HPLC-MS/MS and its application to pharmacokinetic study. | Ponnuru, VS., et al. 2011. Anal Bioanal Chem. 401: 2539-48. PMID: 21892641
- Naratriptan mitigates CGRP1-associated motor neuron degeneration caused by an expanded polyglutamine repeat tract. | Minamiyama, M., et al. 2012. Nat Med. 18: 1531-8. PMID: 23023499
- Formulation, preparation, and evaluation of novel orally disintegrating tablets containing taste-masked naproxen sodium granules and naratriptan hydrochloride. | Stange, U., et al. 2014. J Pharm Sci. 103: 1233-45. PMID: 24532095
- Preparation, characterization and buccal permeation of naratriptan. | Sattar, M., et al. 2015. Int J Pharm. 493: 146-51. PMID: 26196276
- Development and Validation of Stability-Indicating HPTLC Method for Estimation of Naratriptan Hydrochloride in Its Pharmaceutical Dosage Form and Its Content Uniformity Testing. | Prajapati, PB., et al. 2016. J Chromatogr Sci. 54: 1129-36. PMID: 27406125
- Preparation and Optimization of Fast Dissolving Film of Naratr iptan Hydrochloride. | Krishna, KD., et al. 2017. Recent Pat Drug Deliv Formul. 11: 124-131. PMID: 28201962
- Preparation and Optimization of Fast-Disintegrating Tablet Containing Naratriptan Hydrochloride Using D-Optimal Mixture Design. | Omar, SM., et al. 2018. AAPS PharmSciTech. 19: 2472-2487. PMID: 29869307
- Characterization of binding, functional activity, and contractile responses of the selective 5-HT1F receptor agonist lasmiditan. | Rubio-Beltrán, E., et al. 2019. Br J Pharmacol. 176: 4681-4695. PMID: 31418454
- The photoredox-catalyzed hydrosulfamoylation of styrenes and its application in the novel synthesis of naratriptan. | Zhang, M., et al. 2021. Chem Commun (Camb). 57: 9140-9143. PMID: 34498639
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Naratriptan Hydrochloride, 10 mg | sc-212362 | 10 mg | $105.00 |