Molecular structure of Naphthol AS-D acetate, CAS Number: 528-66-5
Naphthol AS-D acetate (CAS 528-66-5)
Alternate Names:
3-(Acetyloxy)-N-(2-methylphenyl)-2-naphthalenecarboxamide
Application:
Naphthol AS-D acetate is a substrate for histochemical localization of esterases
CAS Number:
528-66-5
Molecular Weight:
319.35
Molecular Formula:
C20H17NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Naphthol AS-D acetate, a synthetic compound, has been utilized in scientific research for several decades. Derived from acetylcholine, a naturally occurring compound, it has found application in synthesizing various compounds. Acting as an agonist of the acetylcholine receptor, 2-[N-(o-Methylphenyl)carbamoyl]-3-naphthyl acetate facilitates the transmission of acetylcholine′s effects on the nervous system. Binding to the receptor, it triggers a signaling cascade, resulting in the release of neurotransmitters like glutamate and GABA. This mechanism subsequently enhances neuronal activity and modulates synaptic plasticity.
Naphthol AS-D acetate (CAS 528-66-5) References
- [Chronorogical changes in activities of various enzymes including beta-galactosidase and naphthol AS-D acetate esterase of the mononuclear phagocytes in tuberculosis lesions (author's transl)]. | Tsuda, T., et al. 1978. Kekkaku. 53: 419-24. PMID: 100645
- Chronologic changes of activities of naphthol AS-D acetate esterase and other nonspecific esterases in the mononuclear phagocytes of tuberculous lesions. | Tsuda, T., et al. 1979. Am J Pathol. 97: 235-46. PMID: 118673
- Genetically defined lysosomal acetylesterase EC 3.1.1.6 in the cauda epididymidis of mouse, rat, and man. | Trefzger, J., et al. 1992. Histochemistry. 98: 373-9. PMID: 1338066
- Isolation of osteoclasts from Pagetic bone tissue: morphometry and cytochemistry on isolated cells. | Basle, MF., et al. 1988. Bone. 9: 1-6. PMID: 2837260
- Nonspecific esterase of acute promyelocytic leukemia (M3). | Matsuo, T., et al. 1988. Am J Hematol. 29: 148-51. PMID: 3189310
- A biochemical study of non-specific esterases from plant cells, employing the histochemical substrate, naphthol AS-D acetate. | James, DJ. and Smith, AR. 1974. Histochem J. 6: 7-23. PMID: 4130632
- Monocytopoiesis in normal man: pool size, proliferation activity and DNA synthesis time of promonocytes. | Meuret, G., et al. 1975. Acta Haematol. 54: 261-70. PMID: 809965
- Splenic hemangiosarcoma with sinus endothelial differentiation. | Takato, H., et al. 1993. Acta Pathol Jpn. 43: 702-8. PMID: 8310831
Substrate of:
Enzyme.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Naphthol AS-D acetate, 5 g | sc-250551 | 5 g | $575.00 |