Molecular structure of Naphthofluorescein, CAS Number: 61419-02-1
Naphthofluorescein (CAS 61419-02-1)
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Alternate Names:
CCG 8295
Application:
Naphthofluorescein is a furin inhibitor
CAS Number:
61419-02-1
Purity:
≥95%
Molecular Weight:
432.4
Molecular Formula:
C28H16O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Naphthofluorescein inhibits the invasion of Matrigel by the human fibrosarcoma cell line, HT1080. Naphthofluorescein is an inhibitor of Furin. The effects of this furin inhibitor on other furin-mediated processes are still unknown. It has a high affinity for proteins and other molecules, which allows it to bind to them and interact with them. When Naphthofluorescein binds to a molecule, it can alter its structure and function. Naphthofluorescein is also known for its fluorescent properties. It belongs to the family of fluorescein dyes.
Naphthofluorescein (CAS 61419-02-1) References
- Synthesis and characterization of fluorescent cobalamin (CobalaFluor) derivatives for imaging. | Smeltzer, CC., et al. 2001. Org Lett. 3: 799-801. PMID: 11263885
- A phosphinate-based red fluorescent probe for imaging the superoxide radical anion generated by RAW264.7 macrophages. | Xu, K., et al. 2007. Chembiochem. 8: 453-8. PMID: 17238211
- One-Pot Synthesis of New Symmetric and Asymmetric Xanthene Dyes. | Hilderbrand, SA. and Weissleder, R. 2007. Tetrahedron Lett. 48: 4383-4385. PMID: 19834587
- Exhaustive syntheses of naphthofluoresceins and their functions. | Azuma, E., et al. 2012. J Org Chem. 77: 3492-500. PMID: 22428609
- Monitoring the cytosolic entry of cell-penetrating peptides using a pH-sensitive fluorophore. | Qian, Z., et al. 2015. Chem Commun (Camb). 51: 2162-5. PMID: 25554998
- A near-infrared fluorescent probe based on chloroacetate modified naphthofluorescein for selectively detecting cysteine/homocysteine and its application in living cells. | Wang, J., et al. 2016. Photochem Photobiol Sci. 15: 1393-1399. PMID: 27714261
- A water-soluble near-infrared fluorescent probe for specific Pd2+ detection. | Wen, J., et al. 2018. Bioorg Med Chem. 26: 931-937. PMID: 29254898
- Development of fluorinated naphthofluoresceins for Cerenkov imaging. | Arroyo, AD., et al. 2019. J Fluor Chem. 225: 27-34. PMID: 31427828
- Furin Inhibitors Block SARS-CoV-2 Spike Protein Cleavage to Suppress Virus Production and Cytopathic Effects. | Cheng, YW., et al. 2020. Cell Rep. 33: 108254. PMID: 33007239
- Pharmacological inhibition of Mint3 attenuates tumour growth, metastasis, and endotoxic shock. | Sakamoto, T., et al. 2021. Commun Biol. 4: 1165. PMID: 34621018
- COVID-19 liver and gastroenterology findings: An in silico analysis of SARS-CoV-2 interactions with liver molecules. | Peiter, GC., et al. 2022. World J Hepatol. 14: 1131-1141. PMID: 35978663
- Mint3 as a Potential Target for Cooling Down HIF-1α-Mediated Inflammation and Cancer Aggressiveness. | Tanaka, N. and Sakamoto, T. 2023. Biomedicines. 11: PMID: 36831085
Inhibitor of:
Furin, and PC5/6.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Naphthofluorescein, 1 mg | sc-205413 | 1 mg | $22.00 | |||
Naphthofluorescein, 5 mg | sc-205413A | 5 mg | $45.00 | |||
Naphthofluorescein, 100 mg | sc-205413B | 100 mg | $88.00 |