Date published: 2025-10-15

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Nα-(2-Naphthalenesulfonylglycyl)-4-amidino-D,L-phenylalaninepiperidide (CAS 86125-48-6)

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Alternate Names:
(±)-N-[1-[[4-(Aminoiminomethyl)phenyl]methyl]-2-oxo-2-(1-piperidinyl)ethyl]-2-[(2-naphthalenylsulfonyl)amino]acetamide; α-NAPAP
Application:
CAS Number:
86125-48-6
Molecular Weight:
521.63
Molecular Formula:
C27H31N5O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Nalpha-(2-Naphthalenesulfonylglycyl)-4-amidino-D,L-phenylalaninepiperidide is a selective inhibitor of thrombins. This compound belongs to a class of serine protease inhibitors. As a serine protease inhibitor, this compound is valuable for studying the regulation of proteases involved in various physiological processes. In vitro investigations have demonstrated that Nα-(2-Naphthalenesulfonylglycyl)-4-amidino-D,L-phenylalaninepiperidide exhibits the ability to impede platelet aggregation and fibrin formation, which are processes involved in blood clot formation.


Nα-(2-Naphthalenesulfonylglycyl)-4-amidino-D,L-phenylalaninepiperidide (CAS 86125-48-6) References

  1. Differentiation of thrombin- and factor Xa-related amidolytic activity in plasma by means of a synthetic thrombin inhibitor.  |  Svendsen, L., et al. 1984. Thromb Res. 34: 457-62. PMID: 6377574

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Nα-(2-Naphthalenesulfonylglycyl)-4-amidino-D,L-phenylalaninepiperidide, 1 mg

sc-208083
1 mg
$296.00