Nα-(2,4-Dinitro-5-fluorophenyl)-L-valinamide (CAS 132679-61-9)
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Nα-(2,4-Dinitro-5-fluorophenyl)-L-valinamide is a chiral derivatizing agent (chiral Sanger′s Reagent) used in the determinimation of enantiomeric purity of amino acids with HPLC. This analogue of Marfey′s reagent can also be used with amines. Nα-(2,4-Dinitro-5-fluorophenyl)-L-valinamide, an organic compound with a carbon-nitrogen-fluorine-oxygen-hydrogen backbone, proves to be a versatile and valuable substance widely employed in scientific research and laboratory experiments. With its diverse applications, this compound serves as a highly efficient reagent for various reactions, prompting extensive investigations into its structural properties and mechanism of action. It finds utility in numerous studies, including the synthesis of arylboronic acids, chiral compounds, and organometallic compounds, showcasing its broad range of uses and significance in scientific endeavors.
Nα-(2,4-Dinitro-5-fluorophenyl)-L-valinamide (CAS 132679-61-9) References
- An improved solid-phase methodology for the synthesis of putative hexa- and heptapeptide intermediates in vancomycin biosynthesis. | Bo Li, D. and Robinson, JA. 2005. Org Biomol Chem. 3: 1233-9. PMID: 15785812
- Halogenated cyclic peptides isolated from the sponge Corticium sp. | Laird, DW., et al. 2007. J Nat Prod. 70: 741-6. PMID: 17391049
- Symplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine Cyanobacterium Symploca sp. | Linington, RG., et al. 2008. J Nat Prod. 71: 22-7. PMID: 18163584
- Scopularides A and B, cyclodepsipeptides from a marine sponge-derived fungus, Scopulariopsis brevicaulis. | Yu, Z., et al. 2008. J Nat Prod. 71: 1052-4. PMID: 18412398
- Palmyramide A, a cyclic depsipeptide from a Palmyra Atoll collection of the marine cyanobacterium Lyngbya majuscula. | Taniguchi, M., et al. 2010. J Nat Prod. 73: 393-8. PMID: 19839606
- Freezing effect on chirality amplification of L-asparagine by crystallization of the racemate in preferential condition. | Vajda, T. and Hollósi, MM. 2011. Cryo Letters. 32: 447-50. PMID: 22227704
- Mechanistic Investigations of PoyD, a Radical S-Adenosyl-l-methionine Enzyme Catalyzing Iterative and Directional Epimerizations in Polytheonamide A Biosynthesis. | Parent, A., et al. 2018. J Am Chem Soc. 140: 2469-2477. PMID: 29253341
- Insights into Pipecolic Acid Biosynthesis in Huperzia serrata. | Xu, B., et al. 2018. Org Lett. 20: 2195-2198. PMID: 29589944
- New 3-Hydroxyquinaldic Acid Derivatives from Cultures of the Marine Derived Actinomycete Streptomyces cyaneofuscatus M-157. | Ortiz-López, FJ., et al. 2018. Mar Drugs. 16: PMID: 30297652
- The structure of PghL hydrolase bound to its substrate poly-γ-glutamate. | Ramaswamy, S., et al. 2018. FEBS J. 285: 4575-4589. PMID: 30387270
- Enantioselective Synthesis of Pharmaceutically Active γ-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions. | Biewenga, L., et al. 2019. ACS Catal. 9: 1503-1513. PMID: 30740262
- A sensitive HPLC-MS/MS method for the detection, resolution and quantitation of cathinone enantiomers in horse blood plasma and urine. | Loganathan, D., et al. 2021. Anal Bioanal Chem. 413: 2147-2161. PMID: 33517480
- Euglenatides, Potent Antiproliferative Cyclic Peptides Isolated from the Freshwater Photosynthetic Microalga Euglena gracilis. | Aldholmi, M., et al. 2022. Angew Chem Int Ed Engl. 61: e202203175. PMID: 35325497
- Chiral derivatization-enabled discrimination and on-tissue detection of proteinogenic amino acids by ion mobility mass spectrometry. | Xie, C., et al. 2022. Chem Sci. 13: 14114-14123. PMID: 36540812
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nα-(2,4-Dinitro-5-fluorophenyl)-L-valinamide, 100 mg | sc-253172 | 100 mg | $54.00 |