Molecular structure of Naloxonazine dihydrochloride, CAS Number: 880759-65-9
Naloxonazine dihydrochloride (CAS 880759-65-9)
Alternate Names:
bis[(5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene]hydrazone dihydrochloride
CAS Number:
880759-65-9
Purity:
≥95%
Molecular Weight:
723.69
Molecular Formula:
C38H42N4O6•2HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
A potent opioid antagonist that is selective for µ1 opioid receptors.
Naloxonazine dihydrochloride (CAS 880759-65-9) References
Sakurada, S., et al., Differential antagonism of endomorphin-1 and endomorphin-2 spinal antinociception by naloxonazine and 3-methoxynaltrexone. Brain Res. 881, 1-8, (2000) Piepponen, T.P., et al., Involvement of opioid µ1-receptors in opioid-induced acceleration of striatal and limbic dopaminergic transmission. Pharmacol. Biochem. Behav. 63, 245-252, (1999) Pick, C.G., et al., Comparison of naloxonazine and β-funaltrexamine antagonism of µ1 and µ2 opioid actions. Life Sci. 48, 2005-2011, (1991) Cruciani, et al., Naloxonazine effects on the interaction of enkephalin analogs with µ1µ and δ opioid binding sites in rat brain membranes. J. Pharmacol. Exp. Ther. 242, 15-20, (1987)Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Naloxonazine dihydrochloride, 10 mg | sc-253177 | 10 mg | $88.00 | |||
Naloxonazine dihydrochloride, 50 mg | sc-253177A | 50 mg | $327.00 |