Nafcillin sodium salt (CAS 985-16-0)
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Nafcillin sodium salt, an analog of penicillin, is extensively used in scientific research. In microbiology, it is a reference compound for studying bacterial resistance mechanisms, particularly among Staphylococcus species. Researchers delve into how this compound interacts with penicillin-binding proteins and how mutations in these proteins can lead to antibiotic resistance. In the field of analytical chemistry, nafcillin sodium salt is used to develop and validate analytical methods for detecting and quantifying antibiotics in various samples, which is for monitoring antibiotic levels in the environment. Environmental scientists also study the degradation and persistence of nafcillin in water systems to understand the impact of antibiotics on aquatic ecosystems and to develop strategies for the removal of such contaminants. Additionally, it serves as a model compound in studies aimed at improving the efficacy and stability of beta-lactam compounds.
Nafcillin sodium salt (CAS 985-16-0) References
- Role of surface adsorption and porosity features in the molecular recognition ability of imprinted sol-gels. | Guardia, L., et al. 2008. Biosens Bioelectron. 23: 1101-8. PMID: 18164194
- Nafcillin-loaded PLGA nanoparticles for treatment of osteomyelitis. | Pillai, RR., et al. 2008. Biomed Mater. 3: 034114. PMID: 18708713
- Identification and species similarity of OATP transporters responsible for hepatic uptake of beta-lactam antibiotics. | Nakakariya, M., et al. 2008. Drug Metab Pharmacokinet. 23: 347-55. PMID: 18974612
- Subinhibitory fluoroquinolone exposure selects for reduced beta-lactam susceptibility in methicillin-resistant Staphylococcus aureus and alterations in the SOS-mediated response. | Tattevin, P., et al. 2009. Res Microbiol. 160: 187-92. PMID: 19366630
- Lysostaphin eradicates established Staphylococcus aureus biofilms in jugular vein catheterized mice. | Kokai-Kun, JF., et al. 2009. J Antimicrob Chemother. 64: 94-100. PMID: 19398455
- Epidemiology of community-onset Staphylococcus aureus infections in pediatric patients: an experience at a Children's Hospital in central Illinois. | Mongkolrattanothai, K., et al. 2009. BMC Infect Dis. 9: 112. PMID: 19607683
- Nafcillin-Induced Allergic Eosinophilic Cholestatic Hepatitis. | Guido, MV., et al. 2017. Gastroenterology Res. 10: 202-207. PMID: 28725311
- The Cefazolin Inoculum Effect Is Associated With Increased Mortality in Methicillin-Susceptible Staphylococcus aureus Bacteremia. | Miller, WR., et al. 2018. Open Forum Infect Dis. 5: ofy123. PMID: 29977970
- Data on treatment of nafcillin and ampicillin antibiotics in water by sonochemistry. | Montoya-Rodríguez, DM., et al. 2020. Data Brief. 29: 105361. PMID: 32195299
- Genetic Determinants Enabling Medium-Dependent Adaptation to Nafcillin in Methicillin-Resistant Staphylococcus aureus. | Salazar, MJ., et al. 2020. mSystems. 5: PMID: 32234776
- A comparison of different antibiotic regimens for the treatment of infective endocarditis. | Martí-Carvajal, AJ., et al. 2020. Cochrane Database Syst Rev. 5: CD009880. PMID: 32407558
- Ceftriaxone versus antistaphylococcal antibiotics for definitive treatment of methicillin-susceptible Staphylococcus aureus infections: a systematic review and meta-analysis. | Yetmar, ZA., et al. 2022. Int J Antimicrob Agents. 59: 106486. PMID: 34839007
- Safety and Efficacy of Nafcillin for Empiric Therapy of Late-Onset Sepsis in the NICU. | Magers, J., et al. 2022. Pediatrics. 149: PMID: 35380005
- Nafcillin Augmentation of Daptomycin and Cathelicidin LL-37 Killing of Methicillin-resistant Staphylococcus epidermidis: Foundations of Successful Therapy of Endocarditis. | Catteau, L., et al. 2023. Int J Antimicrob Agents. 61: 106758. PMID: 36775256
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nafcillin sodium salt, 1 g | sc-279902 | 1 g | $73.00 |