NAEPA (CAS 24435-25-4)
Application:
NAEPA is a selective EDG-2 (LPA1) receptor agonist as well as LPA mimetic
CAS Number:
24435-25-4
Molecular Weight:
405.51
Molecular Formula:
C20H40NO5P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
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SDS & Certificate of Analysis
NAEPA is a selective EDG-2 (LPA1) receptor agonist as well as LPA mimetic.
NAEPA (CAS 24435-25-4) References
- Lysophosphatidic acid stimulates prostaglandin E2 production in cultured stromal endometrial cells through LPA1 receptor. | Woclawek-Potocka, I., et al. 2009. Exp Biol Med (Maywood). 234: 986-93. PMID: 19491366
- Pharmacological tools for lysophospholipid GPCRs: development of agonists and antagonists for LPA and S1P receptors. | Im, DS. 2010. Acta Pharmacol Sin. 31: 1213-22. PMID: 20729877
- Synthesis and structure-activity relationships of tyrosine-based inhibitors of autotaxin (ATX). | East, JE., et al. 2010. Bioorg Med Chem Lett. 20: 7132-6. PMID: 20951039
- Development of a phosphatase-resistant, L-tyrosine derived LPA1/LPA3 dual antagonist. | East, JE., et al. 2011. Medchemcomm. 2: 325-330. PMID: 22180836
- Serotonergic neuron regulation informed by in vivo single-cell transcriptomics. | Spaethling, JM., et al. 2014. FASEB J. 28: 771-80. PMID: 24192459
- Transient stretch induces cytoskeletal fluidization through the severing action of cofilin. | Lan, B., et al. 2018. Am J Physiol Lung Cell Mol Physiol. 314: L799-L807. PMID: 29345194
- Impact of organic carbon acquisition on growth and functional biomolecule production in diatoms. | Marella, TK., et al. 2021. Microb Cell Fact. 20: 135. PMID: 34266439
- Human blastoids model blastocyst development and implantation. | Kagawa, H., et al. 2022. Nature. 601: 600-605. PMID: 34856602
- Systematic Review of the Genus Nalepa Reitter, 1887 (Coleoptera, Tenebrionidae, Blaptinae, Blaptini) from the Tibetan Plateau, with Description of Six New Species and Two Larvae. | Li, XM., et al. 2022. Insects. 13: PMID: 35886774
- Entering, Linked with the Sphinx: Lysophosphatidic Acids Everywhere, All at Once, in the Oral System and Cancer. | Cerutis, DR., et al. 2023. Int J Mol Sci. 24: PMID: 37373424
Activator of:
EDG-2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NAEPA, 5 mg | sc-364546 | 5 mg | $500.00 | |||
NAEPA, 25 mg | sc-364546A | 25 mg | $1400.00 |