Date published: 2026-5-18

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NAADP Receptor Modulator (CAS 854091-96-6)

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Alternate Names:
1-Carbamoylmethyl-3-carboxy-pyridinium iodide
Application:
NAADP Receptor Modulator is a cell-permeable nicotinic acid analog
CAS Number:
854091-96-6
Molecular Weight:
308.08
Molecular Formula:
C8H9IN2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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NAADP Receptor Modulator is a cell-permeable nicotinic acid analog that acts as a selective antagonist of NAADP-induced Ca2+ release, while at higher concentrations, also exhibits weak agonistic property towards NAADPR (nicotinic acid adenine dinucleotide phosphate receptor).


NAADP Receptor Modulator (CAS 854091-96-6) References

  1. Cell-permeant small-molecule modulators of NAADP-mediated Ca2+ release.  |  Dowden, J., et al. 2006. Chem Biol. 13: 659-65. PMID: 16793523
  2. Phosphorylation of Nephrin Triggers Ca2+ Signaling by Recruitment and Activation of Phospholipase C-{gamma}1.  |  Harita, Y., et al. 2009. J Biol Chem. 284: 8951-62. PMID: 19179337

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

NAADP Receptor Modulator, 25 mg

sc-222036
25 mg
$250.00