alpha 1 Sodium Potassium ATPase/ATP1A1 Antibody (6D134): sc-71639
- alpha 1 Sodium Potassium ATPase/ATP1A1 Antibody (6D134) is a mouse monoclonal IgG1 provided at 200 µg/ml
- raised against Na+/K+-ATPase α1 of ovine origin
- recommended for detection of Na+/K+-ATPase α1 of mouse, rat and human origin by WB and IF; also reactive with additional species, including and ovine, porcine and canine; non cross-reactive with the α1 isoform in Xenopus or chicken, or the α2 or α3 isoform in rat
- See alpha 1 Sodium Potassium ATPase/ATP1A1 (C464.6): sc-21712 for alpha 1 Sodium Potassium ATPase/ATP1A1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for alpha 1 Sodium Potassium ATPase/ATP1A1 Antibody (6D134). This work is in progress.
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SEE ALSO...
Na+/K+-ATPase α1 Antibody (6D134) is a mouse monoclonal IgG1 antibody specifically raised against the Na+/K+-ATPase α1 subunit of ovine origin. Na+/K+-ATPase α1 monoclonal antibody (6D134) targets the Sodium-Potassium pump, also known as Na+/K+-ATPase, a fundamental membrane protein that maintains cellular ion gradients by actively transporting sodium and potassium ions across the plasma membrane. Na+/K+-ATPase α1 (6D134) antibody recognizes the α1 subunit, a critical component featuring binding sites for ATP and ions, essential for ATPase activity and ion transport function. Structurally, Na+/K+-ATPase is an oligomeric complex composed of multiple subunits, including α, β, and sometimes γ, each contributing to proper folding, stability, and localization within the plasma membrane. The α subunit handles catalytic activity, while the β subunit ensures correct folding and membrane insertion, and the γ subunit modulates ATP affinity in specific tissues. Understanding Na+/K+-ATPase′s intricate structure is crucial as this protein maintains cellular homeostasis, regulates membrane potential, and facilitates secondary active transport processes. Na+/K+-ATPase α1 (6D134) monoclonal antibody is validated for use in western blotting (WB) and immunofluorescence (IF), demonstrating broad reactivity with Na+/K+-ATPase α1 from mouse, rat, human, ovine, porcine, and canine samples. Na+/K+-ATPase α1 (6D134) antibody supports studies in neurobiology, cardiology, and renal physiology, where Sodium-Potassium pump structural integrity is essential for normal cellular function and overall organismal health.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
alpha 1 Sodium Potassium ATPase/ATP1A1 Antibody (6D134) | sc-71639 | 200 µg/ml | $322.00 |