Molecular structure of Na+/H+ Exchanger Isoform-1 Inhibitor, CAS Number: 861218-38-4
Na+/H+ Exchanger Isoform-1 Inhibitor (CAS 861218-38-4)
Alternate Names:
NHE-1 Inhibitor
Application:
Na+/H+ Exchanger Isoform-1 Inhibitor is a acylguanidine compound inhibits NHE-1-mediated pH recovery after acidosis
CAS Number:
861218-38-4
Purity:
≥97%
Molecular Weight:
340.37
Molecular Formula:
C11H8N4OS•CH3SO3H
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Na+/H+ Exchanger Isoform-1 Inhibitor is a cell-permeable acylguanidine compound that inhibits NHE-1-meidated pH recovery after acidosis in PS120 cells. Na+/H+ Exchanger Isoform-1 Inhibitor exhibits cardioprotective efficacy in an isolated rat heart ischemia model in vitro.
Na+/H+ Exchanger Isoform-1 Inhibitor (CAS 861218-38-4) References
- 4-Substituted (benzo[b]thiophene-2-carbonyl)guanidines as novel Na+/H+ exchanger isoform-1 (NHE-1) inhibitors. | Lee, S., et al. 2005. Bioorg Med Chem Lett. 15: 2998-3001. PMID: 15914000
- Neuroprotective properties of Na+/H+-exchanger isoform-1 inhibitor in experimental POAG[J]. | Pobeda A S, Spasov A A, Zhukovskaya O N,. 2023,. Research Results in Pharmacology,. 9(4):: 75-83.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Na+/H+ Exchanger Isoform-1 Inhibitor, 10 mg | sc-222035 | 10 mg | $2440.00 | |||
Na+/H+ Exchanger Isoform-1 Inhibitor, 50 mg | sc-222035A | 50 mg | $1240.00 | |||
Na+/H+ Exchanger Isoform-1 Inhibitor, 100 mg | sc-222035B | 100 mg | $2000.00 |