Date published: 2026-5-19

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N6-p-Sulfophenyladenosine sodium salt (CAS 143668-15-9)

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Application:
N6-p-Sulfophenyladenosine sodium salt is an Adenosine A1-R agonist
CAS Number:
143668-15-9
Purity:
≥95%
Molecular Weight:
445.38
Molecular Formula:
C16H16N5O7S•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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This product is an A1 adenosine receptor agonist.


N6-p-Sulfophenyladenosine sodium salt (CAS 143668-15-9) References

  1. Role of peripheral adenosine A(1) receptors in the regulation of sleep apneas in rats.  |  Carley, DW. and Radulovacki, M. 1999. Exp Neurol. 159: 545-50. PMID: 10506526
  2. Microinjection of an adenosine A1 agonist into the medial pontine reticular formation increases tail flick latency to thermal stimulation.  |  Tanase, D., et al. 2002. Anesthesiology. 97: 1597-601. PMID: 12459690
  3. Adenosinergic mechanisms underlying recovery of diaphragm motor function following upper cervical spinal cord injury: potential therapeutic implications.  |  Nantwi, KD. and Goshgarian, HG. 2005. Neurol Res. 27: 195-205. PMID: 15829183
  4. Sleep, anesthesiology, and the neurobiology of arousal state control.  |  Lydic, R. and Baghdoyan, HA. 2005. Anesthesiology. 103: 1268-95. PMID: 16306742
  5. Influence of adenosine A(1)-receptor blockade and vagotomy on the gasping and heart rate response to hypoxia in rats during early postnatal maturation.  |  Fewell, JE., et al. 2007. J Appl Physiol (1985). 103: 1234-41. PMID: 17641210
  6. Leptin replacement restores supraspinal cholinergic antinociception in leptin-deficient obese mice.  |  Wang, W., et al. 2009. J Pain. 10: 836-43. PMID: 19380255
  7. Thermal nociception is decreased by hypocretin-1 and an adenosine A1 receptor agonist microinjected into the pontine reticular formation of Sprague Dawley rat.  |  Watson, SL., et al. 2010. J Pain. 11: 535-44. PMID: 20015707
  8. Adenosine A(1) receptors in the central nervous system: their functions in health and disease, and possible elucidation by PET imaging.  |  Paul, S., et al. 2011. Curr Med Chem. 18: 4820-35. PMID: 21919845
  9. Negative reinforcement reveals non-evoked ongoing pain in mice with tissue or nerve injury.  |  He, Y., et al. 2012. J Pain. 13: 598-607. PMID: 22609247
  10. Neuronal mechanisms of adenosine A2A receptors in the loss of consciousness induced by propofol general anesthesia with functional magnetic resonance imaging.  |  Chen, L., et al. 2021. J Neurochem. 156: 1020-1032. PMID: 32785947
  11. p-SPA, a peripheral adenosine A1 analogue, reduces sleep apneas in rats.  |  Monti, D., et al. 1996. Pharmacol Biochem Behav. 53: 341-5. PMID: 8808142
  12. Reduced adenosine A1 receptor and G alpha protein coupling in rat ventricular myocardium during aging.  |  Cai, G., et al. 1997. Circ Res. 81: 1065-71. PMID: 9400388

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N6-p-Sulfophenyladenosine sodium salt, 25 mg

sc-301454
25 mg
$168.00