N6-Methyl-2′-deoxyadenosine (CAS 2002-35-9)
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N6-Methyl-2′-deoxyadenosine (m6dA) represents a modified version of adenosine, a nucleoside present in DNA and RNA. This methylated nucleotide plays a pivotal role in various metabolic processes. It serves as a intermediate in the synthesis of DNA and RNA. The scientific community has harnessed the potential of N6-Methyl-2′-deoxyadenosine across multiple research applications. It has emerged as useful for investigating the structure and function of DNA and RNA, as well as exploring the activities of enzymes involved in their synthesis. Moreover, N6-Methyl-2′-deoxyadenosine facilitates the study of gene expression regulation and metabolic pathway control. As a substrate for numerous enzymes engaged in DNA and RNA synthesis, N6-Methyl-2′-deoxyadenosine enables the examination of enzyme structure and function. It also allows researchers to delve into the intricacies of gene expression regulation and metabolic pathway dynamics
N6-Methyl-2′-deoxyadenosine (CAS 2002-35-9) References
- DNA labelling topologies for monitoring DNA-protein complex formation by fluorescence anisotropy. | Bahr, M., et al. 2007. Nucleosides Nucleotides Nucleic Acids. 26: 1581-4. PMID: 18066831
- Pharmacokinetics of 2',3'-dideoxyadenosine in dogs. | Wientjes, MG., et al. 1991. Invest New Drugs. 9: 159-68. PMID: 1908444
- Oligodeoxynucleotides containing N1-methyl-2'-deoxyadenosine and N6-methyl-2'-deoxyadenosine. | Mikhailov, SN., et al. 2009. Curr Protoc Nucleic Acid Chem. Chapter 4: Unit 4.36 1-19. PMID: 19746356
- N 6-Hydroxymethyladenine: a hydroxylation derivative of N6-methyladenine in genomic DNA of mammals. | Xiong, J., et al. 2019. Nucleic Acids Res. 47: 1268-1277. PMID: 30517733
- The DNA modification N6-methyl-2'-deoxyadenosine (m6dA) drives activity-induced gene expression and is required for fear extinction. | Li, X., et al. 2019. Nat Neurosci. 22: 534-544. PMID: 30778148
- Development and validation of monoclonal antibodies against N6-methyladenosine for the detection of RNA modifications. | Matsuzawa, S., et al. 2019. PLoS One. 14: e0223197. PMID: 31577817
- Adenine derivatization for LC-MS/MS epigenetic DNA modifications studies on monocytic THP-1 cells exposed to reference particulate matter. | Cao, X., et al. 2021. Anal Biochem. 618: 114127. PMID: 33571488
- Effect of Genistein Supplementation on the Progression of Neoplasms and the Level of the Modified Nucleosides in Rats With Mammary Cancer. | Banys, K., et al. 2021. In Vivo. 35: 2059-2072. PMID: 34182481
- Global analysis of cytosine and adenine DNA modifications across the tree of life. | Varma, SJ., et al. 2022. Elife. 11: PMID: 35900202
- Effect of Polyphenols and Zinc Co-Supplementation on the Development of Neoplasms in Rats with Breast Cancer. | Jastrzębska, M., et al. 2023. Foods. 12: PMID: 36673448
- Global DNA Adenine Methylation in Caenorhabditis elegans after Multigenerational Exposure to Silver Nanoparticles and Silver Nitrate. | Wamucho, A., et al. 2023. Int J Mol Sci. 24: PMID: 37047139
- N6-methyl-2'-deoxyadenosine promotes self-renewal of BFU-E progenitor in erythropoiesis. | Li, Y., et al. 2023. iScience. 26: 106924. PMID: 37283807
- An altered-specificity mutation in a human POU domain demonstrates functional analogy between the POU-specific subdomain and phage lambda repressor. | Jancso, A., et al. 1994. Proc Natl Acad Sci U S A. 91: 3887-91. PMID: 8171007
- Competitive and selective antagonism of P2Y1 receptors by N6-methyl 2'-deoxyadenosine 3',5'-bisphosphate. | Boyer, JL., et al. 1998. Br J Pharmacol. 124: 1-3. PMID: 9630335
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N6-Methyl-2′-deoxyadenosine, 25 mg | sc-222031 | 25 mg | $362.00 |