Date published: 2025-10-5

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N6-Ethenoadenosine (CAS 39007-51-7)

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CAS Number:
39007-51-7
Purity:
≥95%
Molecular Weight:
291.26
Molecular Formula:
C12H13N5O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N6-Ethenoadenosine (1,N6-EA) is a significant intermediate in the biosynthesis of purine nucleotides and plays a vital role in governing cell growth, proliferation, and differentiation. As a naturally occurring modified adenosine derivative, it serves as a key intermediate in the biosynthesis of purine nucleotides. N6-Ethenoadenosine functions as a competitive inhibitor of adenosine deaminase, an enzyme responsible for the breakdown of adenosine. By inhibiting this enzyme, N6-Ethenoadenosine increases the concentration of adenosine in the body, consequently enhancing the activity of adenosine receptors.


N6-Ethenoadenosine (CAS 39007-51-7) References

  1. Formation of 3,N4-ethenocytidine, 1,N6-ethenoadenosine, and 1,N2-ethenoguanosine in reactions of mucochloric acid with nucleosides.  |  Kronberg, L., et al. 1992. Chem Res Toxicol. 5: 852-5. PMID: 1489937
  2. Incorporation of 1,N6-ethenoadenosine into the 3' terminus of tRNA using T4 RNA ligase. 2. Preparation and ribosome interaction of fluorescent Escherichia coli tRNAMetf.  |  Paulsen, H. and Wintermeyer, W. 1984. Eur J Biochem. 138: 125-30. PMID: 6363067
  3. Molecular properties of 1, N6-ethenoadenosine in comparison with adenosine: self-association, protonation, metal ion complexation, and tryptophan-adduct formation. A study on. epsilon.-adenosine using proton nuclear magnetic resonance, ultraviolet spectrophotometry, and potentiometric pH titration  |  Scheller, K. H., & Sigel, H. 1983. Journal of the American Chemical Society. 105(10): 3005-3014.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N6-Ethenoadenosine, 25 mg

sc-286479
25 mg
$140.00

N6-Ethenoadenosine, 50 mg

sc-286479A
50 mg
$250.00