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(−)-N6-(2-Phenylisopropyl)adenosine is a potent and selective agonist for the adenosine A1 receptor. It functions by binding to and activating the A1 receptor, leading to the inhibition of adenylyl cyclase activity and subsequent reduction in cAMP levels. (−)-N6-(2-Phenylisopropyl)Adenosine modulates neurotransmitter release, particularly inhibiting the release of excitatory neurotransmitters such as glutamate. By doing so, it plays a role in regulating synaptic transmission and neuronal excitability. (−)-N6-(2-Phenylisopropyl)adenosine may have neuroprotective effects, potentially through its ability to reduce excitotoxicity and oxidative stress. Its mechanism of action involves the modulation of ion channels and the regulation of intracellular signaling pathways, ultimately influencing neuronal function and synaptic plasticity. (−)-N6-(2-Phenylisopropyl)adenosine is useful in the studying the physiological and pathophysiological roles of adenosine receptors in the central nervous system.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(−)-N6-(2-Phenylisopropyl)adenosine, 25 mg | sc-253169 | 25 mg | $133.00 |