Date published: 2026-4-24

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N4-Isobutyryl-2′-deoxycytidine (CAS 110522-75-3)

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Alternate Names:
N4-Isobutyryldeoxycytidine
CAS Number:
110522-75-3
Molecular Weight:
297.31
Molecular Formula:
C13H19N3O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N4-Isobutyryl-2′-deoxycytidine is a nucleoside analogue that has gained attention in laboratory experiments for its wide range of scientific applications. Serving as a structural analogue of the nucleoside deoxycytidine, Ibu-dC exhibits distinctive biochemical effects. Scientific investigations have N4-Isobutyryl-2′-deoxycytidine in various fields, including gene expression and regulation and cell signaling. It has proven instrumental in elucidating the regulation of gene expression by inhibiting the activity of specific enzymes involved in transcriptional regulation. Its interaction with receptors and signaling molecules has facilitated investigations into cell signaling pathways. By interacting with specific enzymes, receptors, and DNA-binding proteins, N4-Isobutyryl-2′-deoxycytidine influences transcriptional regulation and offers insights into gene-related processes.


N4-Isobutyryl-2′-deoxycytidine (CAS 110522-75-3) References

  1. Novel phosphoramidite building blocks in synthesis and applications toward modified oligonucleotides.  |  Venkatesan, N., et al. 2003. Curr Med Chem. 10: 1973-91. PMID: 12871099
  2. YqfB protein from Escherichia coli: an atypical amidohydrolase active towards N4-acylcytosine derivatives.  |  Stanislauskienė, R., et al. 2020. Sci Rep. 10: 788. PMID: 31964920
  3. The final deprotection step in oligonucleotide synthesis is reduced to a mild and rapid ammonia treatment by using labile base-protecting groups.  |  Schulhof, JC., et al. 1987. Nucleic Acids Res. 15: 397-416. PMID: 3822812
  4. Deprotection of methylphosphonate oligonucleotides using a novel one-pot procedure.  |  Hogrefe, RI., et al. 1993. Nucleic Acids Res. 21: 2031-8. PMID: 8502543

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N4-Isobutyryl-2′-deoxycytidine, 100 mg

sc-222028
100 mg
$170.00

N4-Isobutyryl-2′-deoxycytidine, 250 mg

sc-222028A
250 mg
$300.00