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N4-Benzoyl-2′-deoxycytidine (CAS 4836-13-9)

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Alternate Names:
N-Benzoyl-2-Deoxy-Cytidine; NBz-2′-dC
CAS Number:
4836-13-9
Molecular Weight:
331.32
Molecular Formula:
C16H17N3O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N4-Benzoyl-2′-deoxycytidine, a synthetic nucleoside analog derived from natural deoxycytidine, holds significance as a tool in biochemistry and molecular biology research. It has been employed in studying DNA and RNA, including their structure, function, and regulatory mechanisms. Furthermore, N4-Benzoyl-2′-deoxycytidine has been instrumental in investigating gene expression, deciphering protein-DNA interactions, and unraveling the intricate mechanisms governing DNA replication and repair.


N4-Benzoyl-2′-deoxycytidine (CAS 4836-13-9) References

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  2. Formation of N-branched oligonucleotides as by-products in solid-phase oligonucleotide synthesis.  |  Cazenave, C., et al. 2006. Oligonucleotides. 16: 181-5. PMID: 16764541
  3. Convenient syntheses of 3'-amino-2',3'-dideoxynucleosides, their 5'-monophosphates, and 3'-aminoterminal oligodeoxynucleotide primers.  |  Eisenhuth, R. and Richert, C. 2009. J Org Chem. 74: 26-37. PMID: 19053612
  4. Studies on 2',3'-dideoxy-2',3'-didehydropyrimidine nucleosides. II. N4-benzoyl-2',3'-dideoxy-2',3'-didehydrocytidine as a prodrug of 2',3'-dideoxy-2',3'-didehydrocytidine (DDCN).  |  Kawaguchi, T., et al. 1989. Chem Pharm Bull (Tokyo). 37: 2547-9. PMID: 2557984
  5. Synthesis and selective cleavage of oligodeoxyribonucleotides containing non-chiral internucleotide phosphoramidate linkages.  |  Mag, M. and Engels, JW. 1989. Nucleic Acids Res. 17: 5973-88. PMID: 2771637
  6. Synthetic nucleosides and nucleotides. XXI. On the synthesis and biological evaluations of 2'-deoxy-alpha-D-ribofuranosyl nucleosides and nucleotides.  |  Yamaguchi, T. and Saneyoshi, M. 1984. Chem Pharm Bull (Tokyo). 32: 1441-50. PMID: 6467456
  7. Synthesis and binding properties of oligodeoxynucleotides containing phenylphosphon(othio)ate linkages.  |  Mag, M., et al. 1997. Bioorg Med Chem. 5: 2213-20. PMID: 9459019
  8. Nucleotides. Part XXVII† Bis[2-(p-nitrophenyl)ethyl] Phosphorochloridate, a New Versatile Phosphorylating Agent in Nucleotide Chemistry  |  Frank Himmelsbach, Ramamurthy Charubala, Wolfgang Pfleiderer. 1987. Helvetica Chimica Acta. 70: 1286-1295.
  9. Engineering tethered DNA molecules by the convertible nucleoside approach  |  Andrew M Macmillan, Gregory L Verdine ∗. 1991. Tetrahedron. 47: 2603-2616.
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  11. Solid phase glycosidation of oligonucleotides  |  Matteo Adinolfi, Gaspare Barone, Lorenzo De Napoli, Luigi Guariniello, Alfonso Iadonisi ∗, Gennaro Piccialli. 1999. Tetrahedron Letters. 40: 2607-2610.
  12. New Types of Very Efficient Photolabile Protecting Groups Based upon the [2-(2-Nitrophenyl)propoxy]carbonyl (NPPOC) Moiety  |  Sigrid Bühler, Irene Lagoja, Heiner Giegrich, Klaus-Peter Stengele, Wolfgang Pfleiderer. 2004. Helvetica Chimica Acta. 87: 620-659.
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N4-Benzoyl-2′-deoxycytidine, 5 g

sc-295827
5 g
$122.00

N4-Benzoyl-2′-deoxycytidine, 25 g

sc-295827A
25 g
$316.00