Molecular structure of N4-Aminocytidine, CAS Number: 57294-74-3
N4-Aminocytidine (CAS 57294-74-3)
Alternate Names:
4-Hydrazino-1-pentofuranosyl-2(1H)-pyrimidinone
Application:
N4-Aminocytidine is a mutagen of E. coli and Salmonella typhimurium
CAS Number:
57294-74-3
Purity:
≥95%
Molecular Weight:
258.23
Molecular Formula:
C9H14N4O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
N4-Aminocytidine is a potent mutagen of E. coli and Salmonella typhimurium. N4-Aminocytidine is a modified nucleoside analog that consists of the cytidine base linked to an amino group at the N4 position. It is used in nucleic acid research.
N4-Aminocytidine (CAS 57294-74-3) References
- Inhibitory effect of cadmium and mercury ions on induction of the adaptive response in Escherichia coli. | Takahashi, K., et al. 1991. Mutat Res. 254: 45-53. PMID: 2059244
- Mutagenic nucleoside analog N4-aminocytidine: metabolism, incorporation into DNA, and mutagenesis in Escherichia coli. | Negishi, K., et al. 1988. J Bacteriol. 170: 5257-62. PMID: 3053653
- Induction of mutation in mouse FM3A cells by N4-aminocytidine-mediated replicational errors. | Takahashi, M., et al. 1988. Mol Cell Biol. 8: 347-52. PMID: 3336361
- Mutagenicity of N4-aminocytidine and its derivatives in Chinese hamster lung V79 cells. Incorporation of N4-aminocytosine into cellular DNA. | Nomura, A., et al. 1987. Mutat Res. 177: 283-7. PMID: 3561428
- N4-aminocytidine, a nucleoside analog that has an exceptionally high mutagenic activity. | Negishi, K., et al. 1983. Nucleic Acids Res. 11: 5223-33. PMID: 6224136
- Effects of the umuDC, mucAB, and samAB operons on the mutational specificity of chemical mutagenesis in Escherichia coli: II. Base substitution mutagenesis. | Watanabe, M., et al. 1994. Mutat Res. 314: 39-49. PMID: 7504190
- Effect of Escherichia coli dnaE antimutator mutants on mutagenesis by the base analog N4-aminocytidine. | Schaaper, RM. and Dunn, RL. 1998. Mutat Res. 402: 23-8. PMID: 9675236
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N4-Aminocytidine, 100 mg | sc-222024 | 100 mg | $546.00 | |||
N4-Aminocytidine, 250 mg | sc-222024A | 250 mg | $1150.00 |