N2-Isobutyryl-2′-deoxyguanosine (CAS 68892-42-2)
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N2-Isobutyryl-2′-deoxyguanosine is a compound used in nucleic acid research to study the structure, function, and dynamics of DNA. This modified nucleoside is incorporated into oligonucleotides to investigate the effects of base modifications on DNA stability, replication, and repair processes. In the field of molecular biology, N2-Isobutyryl-2′-deoxyguanosine is used to examine protein-DNA interactions, as the modification can alter binding affinities and specificities. It is also employed in the study of epigenetic modifications and their role in gene regulation. Researchers use this compound to explore the potential of modified nucleosides in the design of molecular probes for the detection of DNA and RNA in various applications, including diagnostics and molecular imaging.
N2-Isobutyryl-2′-deoxyguanosine (CAS 68892-42-2) References
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- The final deprotection step in oligonucleotide synthesis is reduced to a mild and rapid ammonia treatment by using labile base-protecting groups. | Schulhof, JC., et al. 1987. Nucleic Acids Res. 15: 397-416. PMID: 3822812
- Light-directed synthesis of high-density oligonucleotide arrays using semiconductor photoresists. | McGall, G., et al. 1996. Proc Natl Acad Sci U S A. 93: 13555-60. PMID: 8942972
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N2-Isobutyryl-2′-deoxyguanosine, 5 g | sc-295823 | 5 g | $189.00 | |||
N2-Isobutyryl-2′-deoxyguanosine, 25 g | sc-295823A | 25 g | $681.00 |