N1,N8-Diacetylspermidine-d6 (CAS 82414-35-5 (unlabeled))
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N1,N8-Diacetylspermidine-d6 is primarily utilized in research focusing on polyamine metabolism, particularly in the context of cellular regulation and growth. This deuterated compound is especially valuable in studies using stable isotope labeling techniques, where it helps in tracing and quantifying polyamine pathways in various biological systems. Research involving N1,N8-Diacetylspermidine-d6 often explores its role in modulating cellular processes such as proliferation and differentiation. Additionally, it is used in analytical chemistry to develop more precise methods for detecting and quantifying polyamines in complex biological samples. Furthermore, N1,N8-Diacetylspermidine-d6 assists in the investigation of the enzymatic activities involved in the acetylation and deacetylation of polyamines, which are critical for understanding cellular function and regulation.
N1,N8-Diacetylspermidine-d6 (CAS 82414-35-5 (unlabeled)) References
- Two enzyme-linked immunosorbent assay (ELISA) systems for N1,N8-diacetylspermidine and N1,N12-diacetylspermine using monoclonal antibodies. | Hamaoki, M., et al. 2002. J Biochem. 132: 783-8. PMID: 12417029
- Diacetylated derivatives of spermine and spermidine as novel promising tumor markers. | Kawakita, M. and Hiramatsu, K. 2006. J Biochem. 139: 315-22. PMID: 16567395
- Evaluating the utility of N1,N12-diacetylspermine and N1,N8-diacetylspermidine in urine as tumor markers for breast and colorectal cancers. | Umemori, Y., et al. 2010. Clin Chim Acta. 411: 1894-9. PMID: 20655890
- Effect of storage conditions on salivary polyamines quantified via liquid chromatography-mass spectrometry. | Tomita, A., et al. 2018. Sci Rep. 8: 12075. PMID: 30104641
- Design and synthesis of N1,N8-diacetylspermidine analogues having a linker with desired functional groups. | Ohta, R., et al. 2019. Org Biomol Chem. 17: 867-875. PMID: 30628612
- Gender-Related Differences on Polyamine Metabolome in Liquid Biopsies by a Simple and Sensitive Two-Step Liquid-Liquid Extraction and LC-MS/MS. | Samarra, I., et al. 2019. Biomolecules. 9: PMID: 31779105
- Salivary metabolomics with machine learning for colorectal cancer detection. | Kuwabara, H., et al. 2022. Cancer Sci. 113: 3234-3243. PMID: 35754317
- Significance of urinary N1,N8-diacetylspermidine and N1,N12-diacetylspermine as indicators of neoplastic diseases. | Sugimoto, M., et al. 1995. J Cancer Res Clin Oncol. 121: 317-9. PMID: 7768972
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N1,N8-Diacetylspermidine-d6, 1 mg | sc-470940 | 1 mg | $357.00 | |||
N1,N8-Diacetylspermidine-d6, 10 mg | sc-470940A | 10 mg | $2570.00 |