N1-Acetylspermidine Dihydrochloride (CAS 34450-16-3)
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N1-Acetylspermidine Dihydrochloride binds to nicotinic acetylcholine receptors and activates them, leading to the release of calcium ions, which in turn leads to the activation of a variety of intracellular signaling pathways. It also binds to metal ions, forming complexes that can be used to study the structure and function of proteins. It has been found to increase the expression of the enzyme acetylcholinesterase, as well as inhibit the enzyme monoamine oxidase, which is involved in the breakdown of monoamine neurotransmitters such as serotonin and dopamine. N1-Acetylspermidine Dihydrochloride has been used in a variety of scientific research applications. For example, it has been utilized as a ligand in the study of nicotinic acetylcholine receptors, as a reagent in the synthesis of peptides, and as a substrate for the study of enzymes. It has also been employed as a chelating agent for metal ions and as a tool in the study of protein-protein interactions.
N1-Acetylspermidine Dihydrochloride (CAS 34450-16-3) References
- A mechanism of vasodilatory action of polyamines and acetylpolyamines: possible involvement of their Ca2+ antagonistic properties. | Myung, CS., et al. 2000. J Pharm Pharmacol. 52: 695-707. PMID: 10875547
- The role of polyamine reutilization in depletion of cellular stores of polyamines in non-proliferating tissues. | Bolkenius, FN. and Seiler, N. 1987. Biochim Biophys Acta. 923: 125-35. PMID: 3099850
- Liquid chromatography-tandem mass spectrometry based quantification of arginine metabolites including polyamines in different sample matrices. | Langner, M., et al. 2022. J Chromatogr A. 1671: 463021. PMID: 35421734
- Separation of several free polyamines and their acetylated derivatives by ion-pair reversed-phase high performance liquid chromatography. | Aboul-Enein, HY. and al-Duraibi, IA. 1998. Biomed Chromatogr. 12: 291-3. PMID: 9787901
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N1-Acetylspermidine Dihydrochloride, 1 mg | sc-479948A | 1 mg | $173.00 | |||
N1-Acetylspermidine Dihydrochloride, 5 mg | sc-479948 | 5 mg | $357.00 | |||
N1-Acetylspermidine Dihydrochloride, 10 mg | sc-479948B | 10 mg | $637.00 | |||
N1-Acetylspermidine Dihydrochloride, 50 mg | sc-479948C | 50 mg | $2458.00 |