Date published: 2026-2-3

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N-undecanoyl-L-Homoserine lactone (CAS 216596-71-3)

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Alternate Names:
N-[(3S)-tetrahydro-2-oxo-3-furanyl]-undecanamide; C11-HSL
Application:
N-undecanoyl-L-Homoserine lactone is a minor quorum-sensing signaling molecule in P. aeruginosa
CAS Number:
216596-71-3
Molecular Weight:
269.4
Molecular Formula:
C15H27NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-undecanoyl-L-Homoserine lactone possesses a rare odd-numbered acyl carbon chain and may be a minor quorum-sensing signaling molecule in P. aeruginosa strains. N-undecanoyl-L-Homoserine lactone is a naturally occurring compound produced by bacteria, serving as a signaling molecule in inter-bacterial communication. This small molecule is present in numerous bacterial species and has been extensively employed in the investigation of gene expression regulation within bacterial populations.


N-undecanoyl-L-Homoserine lactone (CAS 216596-71-3) References

  1. Synthetic analogues of the bacterial signal (quorum sensing) molecule N-(3-oxododecanoyl)-L-homoserine lactone as immune modulators.  |  Chhabra, SR., et al. 2003. J Med Chem. 46: 97-104. PMID: 12502363
  2. Specificity of acyl-homoserine lactone synthases examined by mass spectrometry.  |  Gould, TA., et al. 2006. J Bacteriol. 188: 773-83. PMID: 16385066
  3. Methylobacterium extorquens AM1 produces a novel type of acyl-homoserine lactone with a double unsaturated side chain under methylotrophic growth conditions.  |  Nieto Penalver, CG., et al. 2006. FEBS Lett. 580: 561-7. PMID: 16412429
  4. Quorum quenching by an N-acyl-homoserine lactone acylase from Pseudomonas aeruginosa PAO1.  |  Sio, CF., et al. 2006. Infect Immun. 74: 1673-82. PMID: 16495538
  5. Messing with bacterial quorum sensing.  |  González, JE. and Keshavan, ND. 2006. Microbiol Mol Biol Rev. 70: 859-75. PMID: 17158701
  6. The biology and future prospects of antivirulence therapies.  |  Cegelski, L., et al. 2008. Nat Rev Microbiol. 6: 17-27. PMID: 18079741
  7. Annotation and quantification of N-acyl homoserine lactones implied in bacterial quorum sensing by supercritical-fluid chromatography coupled with high-resolution mass spectrometry.  |  Hoang, TPT., et al. 2020. Anal Bioanal Chem. 412: 2261-2276. PMID: 31919609
  8. Identification of the metabolites regulated in soybean-Rhizobia symbiosis through solid phase microextraction coupled with LC-MS.  |  Onat, B., et al. 2021. J Chromatogr A. 1641: 461934. PMID: 33611117
  9. Longitudinal metabolic alterations in plasma of rats exposed to low doses of high linear energy transfer radiation.  |  Dissmore, T., et al. 2021. J Environ Sci Health C Toxicol Carcinog. 39: 219-233. PMID: 33902389
  10. Detection of gut microbiota and pathogen produced N-acyl homoserine in host circulation and tissues.  |  Xue, J., et al. 2021. NPJ Biofilms Microbiomes. 7: 53. PMID: 34183673

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-undecanoyl-L-Homoserine lactone, 5 mg

sc-224151
5 mg
$46.00

N-undecanoyl-L-Homoserine lactone, 10 mg

sc-224151A
10 mg
$118.00