Date published: 2025-11-7

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N-succinimidyl propionate (CAS 30364-55-7)

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Alternate Names:
1-(propionyloxy)pyrrolidine-2,5-dione
Application:
N-succinimidyl propionate is a pyrrolidine for research use
CAS Number:
30364-55-7
Molecular Weight:
171.15
Molecular Formula:
C7H9NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-succinimidyl propionate is a reagent frequently employed in the field of bioconjugation, the process of chemically linking two molecules, one of which is typically a biomolecule such as a protein or antibody. Its primary role is to facilitate the covalent attachment of various functional groups, like carboxylates, to amino groups present on biomolecules, which is fundamental in the preparation of conjugates for research in molecular biology and biochemistry. This compound is particularly valued for its efficiency in creating stable amide bonds under mild conditions that preserve the integrity of sensitive biomolecules. Moreover, N-succinimidyl propionate is instrumental in the labeling of proteins with probes or tags, enabling their detection or purification, and is also used in the modification of surfaces, such as those of nanoparticles, to enhance their biocompatibility or to attach targeting ligands.


N-succinimidyl propionate (CAS 30364-55-7) References

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  6. γ-PGA-coated mesoporous silica nanoparticles with covalently attached prodrugs for enhanced cellular uptake and intracellular GSH-responsive release.  |  Du, X., et al. 2015. Adv Healthc Mater. 4: 771-81. PMID: 25582379
  7. Electrostatic interaction of positive charges on the surface of Psb31 with photosystem II in the diatom Chaetoceros gracilis.  |  Nagao, R., et al. 2017. Biochim Biophys Acta Bioenerg. 1858: 779-785. PMID: 28587930
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-succinimidyl propionate, 100 mg

sc-396988A
100 mg
$163.00

N-succinimidyl propionate, 500 mg

sc-396988
500 mg
$306.00