Molecular structure of N-Succinimidoxycarbonyl-β-alanine N-Succinimidyl Ester, CAS Number: 21994-89-8
N-Succinimidoxycarbonyl-β-alanine N-Succinimidyl Ester (CAS 21994-89-8)
Alternate Names:
N-[[N-[(Succinimidooxy)carbonyl]-β-alanyl]oxy]succinimide
Application:
N-Succinimidoxycarbonyl-β-alanine N-Succinimidyl Ester is A short amino reactive homobifunctional crosslinking reagent
CAS Number:
21994-89-8
Purity:
≥97%
Molecular Weight:
327.24
Molecular Formula:
C12H13N3O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
N-Succinimidoxycarbonyl-β-alanine N-Succinimidyl Ester is a short amino reactive homobifunctional crosslinking reagent. N-Succinimidoxycarbonyl-β-alanine N-Succinimidyl Ester, a valuable research compound, finds utility in polymer coupling to proteins. Its significance lies in promoting greater selectivity among the amino groups present in a protein, resulting in a reduced mixture of heterogeneous PEG-protein conjugates. This specificity ensures that only the most nucleophilic and solvent-exposed amines can undergo the desired reaction, leading to improved control over the coupling process.
N-Succinimidoxycarbonyl-β-alanine N-Succinimidyl Ester (CAS 21994-89-8) References
- Anchimeric assistance effect on regioselective hydrolysis of branched PEGs: a mechanistic investigation. | Guiotto, A., et al. 2004. Bioorg Med Chem. 12: 5031-7. PMID: 15351387
- Limitations of N-hydroxysuccinimide esters in affinity chromatography and protein immobilization. | Wilchek, M. and Miron, T. 1987. Biochemistry. 26: 2155-61. PMID: 19552008
- Long-acting growth hormones produced by conjugation with polyethylene glycol. | Clark, R., et al. 1996. J Biol Chem. 271: 21969-77. PMID: 8703002
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Succinimidoxycarbonyl-β-alanine N-Succinimidyl Ester, 25 mg | sc-212275 | 25 mg | $120.00 | |||
N-Succinimidoxycarbonyl-β-alanine N-Succinimidyl Ester, 100 mg | sc-212275A | 100 mg | $204.00 | |||
N-Succinimidoxycarbonyl-β-alanine N-Succinimidyl Ester, 250 mg | sc-212275B | 250 mg | $280.00 | |||
N-Succinimidoxycarbonyl-β-alanine N-Succinimidyl Ester, 1 g | sc-212275C | 1 g | $1062.00 | |||
N-Succinimidoxycarbonyl-β-alanine N-Succinimidyl Ester, 10 g | sc-212275D | 10 g | $10210.00 |