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n-Propionyl coenzyme A lithium salt (CAS 108321-21-7)

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Application:
n-Propionyl coenzyme A lithium salt is the coenzyme A derivative of propionic acid
CAS Number:
108321-21-7
Purity:
≥85%
Molecular Weight:
829.53
Molecular Formula:
C24H40N7O17P3S•Li
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Propionyl coenzyme A lithium salt plays a functional role in cellular metabolism as a key intermediate in the tricarboxylic acid (TCA) cycle. It is involved in the conversion of pyruvate to acetyl-CoA, which is a pivotal step in the generation of energy through oxidative phosphorylation. N-Propionyl coenzyme A lithium salt interacts with cellular components by serving as a substrate for the enzyme pyruvate dehydrogenase, which catalyzes the conversion of pyruvate to acetyl-CoA. Acetyl-CoA enters the TCA cycle, where it undergoes a series of enzymatic reactions to produce NADH and FADH2, which are essential for ATP production in the electron transport chain. By facilitating the conversion of pyruvate to acetyl-CoA, n-Propionyl coenzyme A lithium salt directly influences cellular processes related to energy production and metabolism. Its presence is for the proper functioning of the TCA cycle and the energy metabolism of the cell. N-Propionyl coenzyme A lithium salt plays a fundamental role in cellular metabolism by serving as an important intermediate in the conversion of pyruvate to acetyl-CoA, thereby influencing energy production and metabolic pathways within the cell.


n-Propionyl coenzyme A lithium salt (CAS 108321-21-7) References

  1. LC-MS/MS-based analysis of coenzyme A and short-chain acyl-coenzyme A thioesters.  |  Neubauer, S., et al. 2015. Anal Bioanal Chem. 407: 6681-8. PMID: 26168961
  2. Reaction kinetic analysis of the 3-hydroxypropionate/4-hydroxybutyrate CO2 fixation cycle in extremely thermoacidophilic archaea.  |  Loder, AJ., et al. 2016. Metab Eng. 38: 446-463. PMID: 27771364
  3. Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation.  |  Trefely, S., et al. 2022. Mol Cell. 82: 447-462.e6. PMID: 34856123
  4. Biotin controls intestinal stem cell mitosis and host-microbiome interactions.  |  Neophytou, C. and Pitsouli, C. 2022. Cell Rep. 38: 110505. PMID: 35263602

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

n-Propionyl coenzyme A lithium salt, 5 mg

sc-215475
5 mg
$247.00

n-Propionyl coenzyme A lithium salt, 10 mg

sc-215475A
10 mg
$420.00

n-Propionyl coenzyme A lithium salt, 25 mg

sc-215475B
25 mg
$834.00