Date published: 2026-5-11

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N-Phenacylthiazolium bromide (CAS 5304-34-7)

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CAS Number:
5304-34-7
Purity:
≥97%
Molecular Weight:
284.17
Molecular Formula:
C11H10BrNOS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Phenacylthiazolium bromide is utilized in research focused on its ability to break advanced glycation end-products (AGEs), which are implicated in aging and several chronic diseases. This compound is particularly valuable for studies investigating the chemical pathways and biological effects of AGEs in various tissues and organ systems. Research involving N-Phenacylthiazolium bromide often delves into its potential to improve cellular function and structural integrity by cleaving AGEs, thereby mitigating their deleterious effects. Additionally, it is used in studies aimed at understanding the kinetics and mechanisms of AGE breakage, which is for designing interventions that could manage or mitigate AGE-related pathologies.


N-Phenacylthiazolium bromide (CAS 5304-34-7) References

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  2. Advanced glycation end products: a Nephrologist's perspective.  |  Raj, DS., et al. 2000. Am J Kidney Dis. 35: 365-80. PMID: 10692262
  3. The cross-link breaker, N-phenacylthiazolium bromide prevents vascular advanced glycation end-product accumulation.  |  Cooper, ME., et al. 2000. Diabetologia. 43: 660-4. PMID: 10855541
  4. Effects of advanced glycation end-product inhibition and cross-link breakage in diabetic rats.  |  Oturai, PS., et al. 2000. Metabolism. 49: 996-1000. PMID: 10954016
  5. Glucose-mediated cross-linking of collagen in rat tendon and skin.  |  Mentink, CJ., et al. 2002. Clin Chim Acta. 321: 69-76. PMID: 12031595
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  8. Osseous wound repair under inhibition of the axis of advanced glycation end-products and the advanced glycation end-products receptor.  |  Tsai, SC., et al. 2015. J Formos Med Assoc. 114: 973-80. PMID: 24389269
  9. Soft-tissue wound healing by anti-advanced glycation end-products agents.  |  Chang, PC., et al. 2014. J Dent Res. 93: 388-93. PMID: 24554538
  10. N-Phenacylthiazolium bromide inhibits the advanced glycation end product (AGE)-AGE receptor axis to modulate experimental periodontitis in rats.  |  Chang, PC., et al. 2014. J Periodontol. 85: e268-76. PMID: 24988129
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Phenacylthiazolium bromide, 1 g

sc-500909
1 g
$275.00

N-Phenacylthiazolium bromide, 5 g

sc-500909A
5 g
$709.00

N-Phenacylthiazolium bromide, 25 g

sc-500909B
25 g
$2403.00

N-Phenacylthiazolium bromide, 100 g

sc-500909C
100 g
$5722.00