N-Palmitoyl serinol (CAS 126127-31-9)
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N-Palmitoyl serinol, a molecule combining a fatty acid chain with a serinol backbone, has interest in biochemical research for its role in mimicking sphingolipid behavior. This compound is a focus in studies related to the structure and function of sphingolipids within cellular membranes, contributing to the understanding of membrane dynamics and lipid rafts. It′s especially useful in the exploration of lipid-protein interactions and the stabilization of membrane-associated proteins. Researchers also utilize N-Palmitoyl serinol to investigate the synthesis of glycosphingolipids, which play critical roles in cell recognition and signaling. Additionally, its amphiphilic nature makes it a candidate for creating artificial lipid bilayers or liposomes to study chemical delivery mechanisms, providing a model system to understand how bioactive molecules interact with lipid structures.
N-Palmitoyl serinol (CAS 126127-31-9) References
- Interaction of cholesterol with sphingosine: physicochemical characterization and impact on intestinal absorption. | Garmy, N., et al. 2005. J Lipid Res. 46: 36-45. PMID: 15520452
- Substrate specificity of human ceramide kinase. | Wijesinghe, DS., et al. 2005. J Lipid Res. 46: 2706-16. PMID: 16170208
- Ceramide channels: influence of molecular structure on channel formation in membranes. | Perera, MN., et al. 2012. Biochim Biophys Acta. 1818: 1291-301. PMID: 22365970
- Primary cilia in stem cells and neural progenitors are regulated by neutral sphingomyelinase 2 and ceramide. | He, Q., et al. 2014. Mol Biol Cell. 25: 1715-29. PMID: 24694597
- Commensal bacteria make GPCR ligands that mimic human signalling molecules. | Cohen, LJ., et al. 2017. Nature. 549: 48-53. PMID: 28854168
- GPCRs as an emerging host-directed therapeutic target against mycobacterial infection: From notion to reality. | Naz, F. and Arish, M. 2022. Br J Pharmacol. 179: 4899-4909. PMID: 33150959
- Topical N-palmitoyl serinol, a commensal bacterial metabolite, prevents the development of epidermal permeability barrier dysfunction in a murine model of atopic dermatitis-like skin. | Wen, S., et al. 2021. Can J Vet Res. 85: 201-204. PMID: 34248264
- N-Palmitoyl Serinol Stimulates Ceramide Production through a CB1-Dependent Mechanism in In Vitro Model of Skin Inflammation. | Shin, KO., et al. 2021. Int J Mol Sci. 22: PMID: 34361066
- Optimizing emollient therapy for skin barrier repair in atopic dermatitis. | Elias, PM. 2022. Ann Allergy Asthma Immunol. 128: 505-511. PMID: 35065300
- The Neuroprotective Effect of NEUROMIDE, a Compound Bioidentical to Commensal Bacteria Metabolites. | Seo, Y., et al. 2022. Life (Basel). 12: PMID: 36294963
- Integrated transcriptomic and metabolomic analyses of DNCB-induced atopic dermatitis in mice. | Tang, Y., et al. 2023. Life Sci. 317: 121474. PMID: 36746357
- Gut feeling on bacterial GPCR agonists | Cully, M. 2017. Nature Reviews Drug Discovery. 16(11): 754-754.
- Epidermal Endocannabinoid System (EES) and its Cosmetic Application | Jeong, S., Kim, M. S., Lee, S. H., & Park, B. D. 2019. Cosmetics. 6(2): 33.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Palmitoyl serinol, 10 mg | sc-281092 | 10 mg | $150.00 | |||
N-Palmitoyl serinol, 50 mg | sc-281092A | 50 mg | $600.00 |