N-(p-Coumaroyl) Serotonin (CAS 68573-24-0)
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N-(p-Coumaroyl) serotonin is a phenolic compound that has the interest of researchers for its involvement in plant defense mechanisms and potential signaling roles. In plant biology, it is utilized as a model compound to study the biosynthesis and function of plant natural products, particularly in how plants respond to environmental stressors such as UV radiation and pathogen attack. Its role in the modulation of plant growth and development is also a subject of investigation, as phenolic compounds are known to interact with plant hormones and influence physiological processes. In addition, N-(p-Coumaroyl) serotonin is examined in the context of plant-pollinator interactions, since such secondary metabolites can affect flower and seed chemistry, potentially influencing pollinator behavior and plant reproductive success. Furthermore, its impact on the nutritional quality of plant-derived foods and its potential as a bioactive compound in human nutrition is explored, which contributes to the understanding of food science and human health.
N-(p-Coumaroyl) Serotonin (CAS 68573-24-0) References
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- Multiple mechanisms involved in the inhibition of proinflammatory cytokine production from human monocytes by N-(p-coumaroyl)serotonin and its derivatives. | Takii, T., et al. 2003. Int Immunopharmacol. 3: 273-7. PMID: 12586608
- Inhibitory effect of serotonin derivatives on high glucose-induced adhesion and migration of monocytes on human aortic endothelial cells. | Piga, R., et al. 2009. Br J Nutr. 102: 264-72. PMID: 19222875
- Protective effect of serotonin derivatives on glucose-induced damage in PC12 rat pheochromocytoma cells. | Piga, R., et al. 2010. Br J Nutr. 103: 25-31. PMID: 19747415
- Safflower seed polyphenols (N-(p-coumaroyl)serotonin and N-feruloylserotonin) ameliorate atherosclerosis and distensibility of the aortic wall in Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits. | Katsuda, S., et al. 2009. Hypertens Res. 32: 944-9. PMID: 19763138
- Effect of N-(p-coumaroyl)serotonin and N-feruloylserotonin, major anti-atherogenic polyphenols in safflower seed, on vasodilation, proliferation and migration of vascular smooth muscle cells. | Takimoto, T., et al. 2011. Mol Nutr Food Res. 55: 1561-71. PMID: 21648068
- Preparative Separation of N-Feruloyl Serotonin and N-(p-Coumaroyl) Serotonin from Safflower Seed Meal Using High-Speed Counter-Current Chromatography. | Zhang, Q., et al. 2015. J Chromatogr Sci. 53: 1341-5. PMID: 25744248
- Phytochemistry and Pharmacology of Carthamus tinctorius L. | Zhang, LL., et al. 2016. Am J Chin Med. 44: 197-226. PMID: 27080938
- N-(p-coumaroyl) serotonin inhibits glioblastoma cells growth through triggering S-phase arrest and apoptosis. | Lazari, D., et al. 2017. J Neurooncol. 132: 373-381. PMID: 28365838
- N-(p-coumaroyl) serotonin induces cell cycle arrest and apoptosis in breast cancer cells. | Mitsis, M., et al. 2018. J BUON. 23: 129-133. PMID: 29552772
- Antiproliferative and cytotoxic action of N-(p-coumaroyl) serotonin in lung cancer cells. | Mitsis, M., et al. 2018. J BUON. 23: 1693-1698. PMID: 30610796
- Protective Effects of Serotonin and its Derivatives, N-Feruloylserotonin and N-(p-Coumaroyl) Serotonin, Against Cisplatin-Induced Renal Damage in Mice. | Park, CH., et al. 2019. Am J Chin Med. 47: 369-383. PMID: 30827154
- Serotonin derivative, N-(p-coumaroyl) serotonin, inhibits the production of TNF-alpha, IL-1alpha, IL-1beta, and IL-6 by endotoxin-stimulated human blood monocytes. | Kawashima, S., et al. 1998. J Interferon Cytokine Res. 18: 423-8. PMID: 9660250
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-(p-Coumaroyl) Serotonin, 5 mg | sc-207925 | 5 mg | $160.00 |