Molecular structure of N-Oleoyl-L-serine, CAS Number: 1246302-99-7
N-Oleoyl-L-serine (CAS 1246302-99-7)
Alternate Names:
N-[(9Z)-9-Octadecenoyl]serine
Application:
N-Oleoyl-L-serine is an endogenous lipid used in the study of bioactive N-acyl amides
CAS Number:
1246302-99-7
Molecular Weight:
369.54
Molecular Formula:
C21H39NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
N-Oleoyl-L-serine is an endogenous lipid that has been reported to stimulate bone formation and to inhibit bone resorption. In a study of endogenous amides found in mouse bone, N-Oleoyl-L-serine had the highest activity in an osteoblast proliferation assay. N-Oleoyl-L-serine has been shown to trigger a Gi-protein-coupled receptor and Erk1/2. It also mitigates osteoclast number by promoting osteoclast apoptosis through the inhibition of Erk1/2 phosphorylation and receptor activator of nuclear-κB ligand (RANKL) expression in bone marrow stromal cells and osteoblasts.
N-Oleoyl-L-serine (CAS 1246302-99-7) References
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- The influence of dapagliflozin on cardiac remodeling, myocardial function and metabolomics in type 1 diabetes mellitus rats. | Rodrigues, EA., et al. 2023. Diabetol Metab Syndr. 15: 223. PMID: 37908006
- Liposomes from Lipidonucleotides and from Lipidopeptides[J]. | Bonaccio S, Cescato C, Walde P. 1994: Self-Production of Supramolecular Structures: From Synthetic Structures to Models of Minimal Living Systems,.: 255-259.
- Targeted lipidomics reveals changes in N-acyl serines by acute exposure to an electric field: Molecular insights into the docking of N-18: 1 serine interaction with TRPV1 or PPAR-α[J]. | Nakagawa-Yagi Y, Hara H, Ohto T,. 2019. Integr Mol Med,., 6:: 1-8.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Oleoyl-L-serine, 5 mg | sc-222013 | 5 mg | $46.00 | |||
N-Oleoyl-L-serine, 25 mg | sc-222013A | 25 mg | $247.00 |