Molecular structure of n-Octylglucoside, CAS Number: 29836-26-8
n-Octylglucoside (CAS 29836-26-8)
See product citations (13)
Alternate Names:
OG; Octyl-Glucoside
Application:
n-Octylglucoside is a mild, non-denaturing detergent for the solubilization and reconstitution of membrane-bound proteins
CAS Number:
29836-26-8
Purity:
≥98%
Molecular Weight:
292.4
Molecular Formula:
C14H28O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
n-Octylglucoside is a mild and non-denaturing detergent for the solubilization and reconsititution of membrane bound proteins. Most notable for its ability to be readily removed from final protein extracts via dialysis or gel filtration this ability is due to n-Octylglucoside′s high critical micelle concentration (CMC). The CMC value indicates a detergent′s strength of hydrophobic binding and how readily molecules are incorporated into the micelle. Also useful in 2D electrophoresis and in an immunoprecipitation buffer for the immunopurification of phospho-tyrosine peptides.
n-Octylglucoside (CAS 29836-26-8) References
- Building a thermostable membrane protein. | Zhou, Y. and Bowie, JU. 2000. J Biol Chem. 275: 6975-9. PMID: 10702260
- Reconstitution of hepatitis C virus envelope glycoproteins into liposomes as a surrogate model to study virus attachment. | Lambot, M., et al. 2002. J Biol Chem. 277: 20625-30. PMID: 11937498
- Use of detergents to increase selectivity of immunoprecipitation of tyrosine phosphorylated peptides prior to identification by MALDI quadrupole-TOF MS. | Zhang, G. and Neubert, TA. 2006. Proteomics. 6: 571-8. PMID: 16342243
- A glycosyltransferase-enriched reconstituted membrane system for the synthesis of branched O-linked glycans in vitro. | Susini, S., et al. 2011. Biochim Biophys Acta. 1808: 1509-19. PMID: 21081110
- Reconstitution into liposomes of the glycoprotein of vesicular stomatitis virus by detergent dialysis. | Petri, WA. and Wagner, RR. 1979. J Biol Chem. 254: 4313-6. PMID: 220238
- Depolymerization of solubilized gastric (H+ + K+)-ATPase by n-octylglucoside or cholate. | Soumarmon, A., et al. 1986. Biochim Biophys Acta. 860: 109-17. PMID: 3015211
- Structural Dynamics of the Paddle Motif Loop in the Activated Conformation of KvAP Voltage Sensor. | Das, A., et al. 2020. Biophys J. 118: 873-884. PMID: 31547975
- Conformational heterogeneity of the voltage sensor loop of KvAP in micelles and membranes: A fluorescence approach. | Das, A. and Raghuraman, H. 2021. Biochim Biophys Acta Biomembr. 1863: 183568. PMID: 33529577
- Nanocochleates containing N-Octylglicoside extracted Vibrio cholerae antigens elicited high vibriocidal antibodies titers after intragastric immunization in a mice model. | Tamargo, SB., et al. 2021. Microb Pathog. 156: 104902. PMID: 33930421
- Hydrodynamic properties of monomeric cytochromes P-450LM2 and P-450LM4 in n-octylglucoside solution. | Dean, WL. and Gray, RD. 1982. Biochem Biophys Res Commun. 107: 265-71. PMID: 7126207
- A high-resolution 1H NMR approach for structure determination of membrane peptides and proteins in non-deuterated detergent: application to mastoparan X solubilized in n-octylglucoside. | Seigneuret, M. and Lévy, D. 1995. J Biomol NMR. 5: 345-52. PMID: 7647553
- Synthesis of the photoaffinity label [1'-14C]-6C-(azimethyl)octylglucoside and its reaction with isolated renal brush border membranes. | Kipp, H., et al. 1997. Anal Biochem. 245: 61-8. PMID: 9025969
Inhibitor of:
Baculovirus gp64.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
n-Octylglucoside, 1 g | sc-29103 | 1 g | $97.00 |