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n-Octyl-β-D-thioglucopyranoside (CAS 85618-21-9)

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Alternate Names:
Octyl thioglucoside
Application:
n-Octyl-β-D-thioglucopyranoside is a non-ionic detergent used to isolate membrane proteins from E. coli without inativation
CAS Number:
85618-21-9
Purity:
≥99%
Molecular Weight:
308.4
Molecular Formula:
C14H28O5S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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n-Octyl-beta-D-thioglucopyranoside is a non-ionic detergent that has been used to isolate membrane proteins from E. coli without inactivation. Stable in aqueous solution and easily removed by dialysis. Highly purified and intended for use as a detergent to solubilize membrane-bound proteins in their native state.


n-Octyl-β-D-thioglucopyranoside (CAS 85618-21-9) References

  1. Electrospray mass spectra of three proprietary detergents.  |  Yang-Boja, E., et al. 2000. Anal Biochem. 285: 205-10. PMID: 11017703
  2. Use of octyl beta-thioglucopyranoside in two-dimensional crystallization of membrane proteins.  |  Chami, M., et al. 2001. J Struct Biol. 133: 64-74. PMID: 11356065
  3. Purification of a membrane glycoprotein with an inositol-containing phospholipid anchor from Dictyostelium discoideum.  |  Ti, ZC., et al. 1990. J Biotechnol. 16: 233-43. PMID: 1368595
  4. Effect of NaCl on the self-aggregation of n-octyl beta-D-thioglucopyranoside in aqueous medium.  |  Molina-Bolívar, JA., et al. 2006. J Phys Chem B. 110: 12089-95. PMID: 16800521
  5. Rotational dynamics of coumarin 153 in non-ionic mixed micelles of n-octyl-β-D-thioglucoside and Triton X-100.  |  Carnero Ruiz, C. 2012. Photochem Photobiol Sci. 11: 1331-8. PMID: 22635256
  6. Self-assembly, surface activity and structure of n-octyl-β-D-thioglucopyranoside in ethylene glycol-water mixtures.  |  Ruiz, CC., et al. 2013. Int J Mol Sci. 14: 3228-53. PMID: 23385232
  7. Deuterium NMR Investigation of the lyotropic phases of alkyl β-glycoside/D2O systems.  |  Misran, O., et al. 2013. J Phys Chem B. 117: 7335-44. PMID: 23718628
  8. Characterization of human β,β-carotene-15,15'-monooxygenase (BCMO1) as a soluble monomeric enzyme.  |  Kowatz, T., et al. 2013. Arch Biochem Biophys. 539: 214-22. PMID: 23727499
  9. Structural analysis of rice Os4BGlu18 monolignol β-glucosidase.  |  Baiya, S., et al. 2021. PLoS One. 16: e0241325. PMID: 33471829
  10. Characteristics of n-octyl beta-D-thioglucopyranoside, a new non-ionic detergent useful for membrane biochemistry.  |  Saito, S. and Tsuchiya, T. 1984. Biochem J. 222: 829-32. PMID: 6237644
  11. Use of n-octyl-beta-D-thioglucoside, a new nonionic detergent, for solubilization and reconstitution of membrane proteins.  |  Tsuchiya, T. and Saito, S. 1984. J Biochem. 96: 1593-7. PMID: 6396301
  12. n-alkylglucosides serve as acceptors for galactosyltransferases from rat liver Golgi vesicles.  |  Pohlentz, G., et al. 1995. Biol Chem Hoppe Seyler. 376: 501-5. PMID: 7576249
  13. Bacterial lipopolysaccharide copurifies with plasmid DNA: implications for animal models and human gene therapy.  |  Wicks, IP., et al. 1995. Hum Gene Ther. 6: 317-23. PMID: 7779915
  14. Interaction of octyl-beta-thioglucopyranoside with lipid membranes.  |  Wenk, MR. and Seelig, J. 1997. Biophys J. 73: 2565-74. PMID: 9370450

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

n-Octyl-β-D-thioglucopyranoside, 2 g

sc-281090A
2 g
$100.00

n-Octyl-β-D-thioglucopyranoside, 5 g

sc-281090
5 g
$181.00

n-Octyl-β-D-thioglucopyranoside, 10 g

sc-281090B
10 g
$328.00

n-Octyl-β-D-thioglucopyranoside, 25 g

sc-281090C
25 g
$775.00

n-Octyl-β-D-thioglucopyranoside, 50 g

sc-281090D
50 g
$1359.00