Date published: 2026-4-28

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n-Octyl 4-hydroxybenzoate (CAS 1219-38-1)

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Alternate Names:
4-Hydroxybenzoic acid n-octyl ester
CAS Number:
1219-38-1
Molecular Weight:
250.33
Molecular Formula:
C15H22O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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n-Octyl 4-hydroxybenzoate, an organic compound, finds application as a preservative belonging to the paraben family, a group of compounds frequently employed in the cosmetic industry. This substance acts as a fungicide, bactericide, and anti-microbial agent. Furthermore, it plays a role in researching the toxicity of preservative.


n-Octyl 4-hydroxybenzoate (CAS 1219-38-1) References

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  2. Analysis of additives in dairy products by liquid chromatography coupled to quadrupole-orbitrap mass spectrometry.  |  Jia, W., et al. 2014. J Chromatogr A. 1336: 67-75. PMID: 24607030
  3. Ultrasound-assisted dispersive liquid-liquid microextraction followed by gas chromatography-mass spectrometry for determination of parabens in human breast tumor and peripheral adipose tissue.  |  Shen, X., et al. 2018. J Chromatogr B Analyt Technol Biomed Life Sci. 1096: 48-55. PMID: 30142553
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  5. Effective extraction of fluorescent brightener 52 from foods by in situ formation of hydrophobic deep eutectic solvent.  |  Shi, Y., et al. 2020. Food Chem. 311: 125870. PMID: 31740270
  6. Hydrophobic Deep Eutectic Solvents as Greener Substitutes for Conventional Extraction Media: Examples and Techniques.  |  Devi, M., et al. 2023. ACS Omega. 8: 9702-9728. PMID: 36969397
  7. Preclinical characterization of water-free cyclosporine eye drops - Factors impacting ocular penetration ex vivo and in vivo.  |  Agarwal, P., et al. 2023. Eur J Pharm Biopharm. 188: 100-107. PMID: 37178940
  8. Second harmonic generation measurements of molecular orientation and coadsorption at the interface between two immiscible electrolyte solutions  |  Higgins, D. A., Naujok, R. R., & Corn, R. M. 1993. Chemical physics letters. 213(5-6): 485-490.
  9. Retention indices of phenols for internal standards in reversed-phase high-performance liquid chromatography: application to retention prediction and selectivities of mobile phases and packing materials  |  Yamauchi, S. 1993. Journal of Chromatography A. 635(1): 61-70.
  10. Optical second-harmonic generation measurements of molecular adsorption and orientation at the liquid/liquid electrochemical interface  |  Naujok, R. R., Higgins, D. A., Hanken, D. G., & Com, R. M. 1995. Journal of the Chemical Society, Faraday Transactions. 91(10): 1411-1420.
  11. Investigation of transport across an immiscible liquid/liquid interface. Electrochemical and second harmonic generation studies  |  Crawford, M. J., Frey, J. G., VanderNoot, T. J., & Zhao, Y. 1996. Journal of the Chemical Society, Faraday Transactions. 92(8): 1369-1373.
  12. Synthesis and characterization of liquid crystalline triaryloxy-s-triazines.  |  Gibson, H. W., Dotson, D. L., Marand, H., & Swager, T. M. 1999. Molecular Crystals and Liquid Crystals Science and Technology. Section A. Molecular Crystals and Liquid Crystals. 326(1): 113-138.
  13. Hydrophobic Deep Eutectic Solvents as Greener Substitutes for Conventional Extraction Media: Examples and Techniques  |  Devi, M., Moral, R., Thakuria, S., Mitra, A., & Paul, S. 2023. ACS omega. 8(11): 9702-9728.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

n-Octyl 4-hydroxybenzoate, 25 g

sc-269873
25 g
$78.00