Date published: 2025-11-30

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N-Octanoylglycine (CAS 14246-53-8)

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Alternate Names:
N-(1-Oxooctyl)glycine; Capryloylglycine; Lipacide C 8G
Application:
N-Octanoylglycine is An amphiphilic lipoamino acid.
CAS Number:
14246-53-8
Molecular Weight:
201.26
Molecular Formula:
C10H19NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Octanoylglycine, a medium-chain acyl glycine, is increasingly studied in scientific research due to its unique biochemical properties and applications. As a derivative of fatty acids and glycine, it serves as a valuable compound in the study of lipid metabolism and energy regulation. In research, N-Octanoylglycine is particularly noted for its role in modulating cellular energy metabolism; it acts as a substrate for various enzymes involved in the beta-oxidation pathways. This compound has been employed in studies focusing on mitochondrial function, where it is utilized to investigate the effects of fatty acid derivatives on mitochondrial energy production and regulation. Furthermore, N-Octanoylglycine is explored for its potential as a surfactant and emulsifying agent in pharmaceutical formulations, improving the solubility and stability of hydrophobic compounds. In addition to its biochemical and pharmaceutical applications, this compound is also examined in cosmetic science for its skin-conditioning properties, contributing to moisturization and barrier function enhancement. Researchers value N-Octanoylglycine for its versatility and utility in various scientific domains, including biochemistry, medicine, and cosmetic science, making it a significant subject of study in understanding the complex interactions within cellular metabolism and material science.


N-Octanoylglycine (CAS 14246-53-8) References

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  2. Modulation of plasma and urine metabolome in colorectal cancer survivors consuming rice bran.  |  Zarei, I., et al. 2019. Integr Food Nutr Metab. 6: PMID: 31396400
  3. Untargeted metabolomics for uncovering biological markers of human skeletal muscle ageing.  |  Wilkinson, DJ., et al. 2020. Aging (Albany NY). 12: 12517-12533. PMID: 32580166
  4. Dietary Annatto-Extracted Tocotrienol Reduces Inflammation and Oxidative Stress, and Improves Macronutrient Metabolism in Obese Mice: A Metabolic Profiling Study.  |  Shen, CL., et al. 2021. Nutrients. 13: PMID: 33924335
  5. Spontaneous emergence of membrane-forming protoamphiphiles from a lipid-amino acid mixture under wet-dry cycles.  |  Joshi, MP., et al. 2021. Chem Sci. 12: 2970-2978. PMID: 34164065
  6. ECHDC1 knockout mice accumulate ethyl-branched lipids and excrete abnormal intermediates of branched-chain fatty acid metabolism.  |  Dewulf, JP., et al. 2021. J Biol Chem. 297: 101083. PMID: 34419447
  7. Untargeted metabolomics identifies the potential role of monocarboxylate transporter 6 (MCT6/SLC16A5) in lipid and amino acid metabolism pathways.  |  Ren, T., et al. 2022. Pharmacol Res Perspect. 10: e00944. PMID: 35466588
  8. Cats with Genetic Variants of AGXT2 Respond Differently to a Dietary Intervention Known to Reduce the Risk of Calcium Oxalate Stone Formation.  |  Hall, JA., et al. 2022. Genes (Basel). 13: PMID: 35627178
  9. Short-term periodic restricted feeding elicits metabolome-microbiome signatures with sex dimorphic persistence in primate intervention.  |  Yanai, H., et al. 2024. Nat Commun. 15: 1088. PMID: 38316796
  10. TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models.  |  Wilson, EN., et al. 2024. Nat Neurosci. 27: 873-885. PMID: 38539014

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Octanoylglycine, 5 g

sc-477923
5 g
$311.00