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N-octanoyl-L-Homoserine lactone (CAS 147852-84-4)

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Alternate Names:
C8-HSL; OHL
Application:
N-octanoyl-L-Homoserine lactone is a small signaling molecule involved in quorum sensing
CAS Number:
147852-84-4
Purity:
≥98%
Molecular Weight:
227.30
Molecular Formula:
C12H21NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-octanoyl-L-Homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. The applications of this molecule include regulation of virulence in general. N-Octanoyl-L-homoserine lactone plays a pivotal role in the field of microbial communication, specifically within the context of quorum sensing. Quorum sensing is a bacterial communication process that allows bacterial populations to synchronize their behavior in response to the density of their local population. This communication is facilitated by the production, release, and detection of chemical signal molecules, such as N-Octanoyl-L-homoserine lactone.


N-octanoyl-L-Homoserine lactone (CAS 147852-84-4) References

  1. N-acyl-homoserine lactone inhibition of rhizobial growth is mediated by two quorum-sensing genes that regulate plasmid transfer.  |  Wilkinson, A., et al. 2002. J Bacteriol. 184: 4510-9. PMID: 12142421
  2. Structure of the Escherichia coli quorum sensing protein SdiA: activation of the folding switch by acyl homoserine lactones.  |  Yao, Y., et al. 2006. J Mol Biol. 355: 262-73. PMID: 16307757
  3. The Response of Pseudomonas aeruginosa PAO1 Efflux Pump-Defective Mutants to N-Octanoyl-L-Homoserine Lactone.  |  Yawata, Y., et al. 2009. Microbes Environ. 24: 338-42. PMID: 21566394
  4. Pseudomonas cremoricolorata strain ND07 produces N-acyl homoserine lactones as quorum sensing molecules.  |  Yunos, NY., et al. 2014. Sensors (Basel). 14: 11595-604. PMID: 24984061
  5. Genomic and phenotypic analyses of Serratia fonticola strain GS2: a rhizobacterium isolated from sesame rhizosphere that promotes plant growth and produces N-acyl homoserine lactone.  |  Jung, BK., et al. 2017. J Biotechnol. 241: 158-162. PMID: 27923736
  6. Potential roles of acyl homoserine lactone based quorum sensing in sequencing batch nitrifying biofilm reactors with or without the addition of organic carbon.  |  Sun, Y., et al. 2018. Bioresour Technol. 259: 136-145. PMID: 29549833
  7. Exogenous N-acyl homoserine lactones facilitate microbial adhesion of high ammonia nitrogen wastewater on biocarrier surfaces.  |  Peng, P., et al. 2018. Sci Total Environ. 624: 1013-1022. PMID: 29929218
  8. Characterization of quorum sensing genes and N-acyl homoserine lactones in Citrobacter amalonaticus strain YG6.  |  Kher, HL., et al. 2019. Gene. 684: 58-69. PMID: 30321658
  9. Undesirable effects of exogenous N-acyl homoserine lactones on moving bed biofilm reactor treating medium-strength synthetic wastewater.  |  Fan, X., et al. 2019. Sci Total Environ. 696: 134061. PMID: 31465921
  10. Effects of exogenous N-acyl-homoserine lactones on nutrient removal, sludge properties and microbial community structures during activated sludge process.  |  Yan, X., et al. 2020. Chemosphere. 255: 126945. PMID: 32388260
  11. Quorum-sensing molecules: Sampling, identification and characterization of N-acyl-homoserine lactone in Vibrio sp.  |  Laj, N., et al. 2022. Saudi J Biol Sci. 29: 2733-2737. PMID: 35531216
  12. Multiple N-acyl-L-homoserine lactone autoinducers of luminescence in the marine symbiotic bacterium Vibrio fischeri.  |  Kuo, A., et al. 1994. J Bacteriol. 176: 7558-65. PMID: 8002580
  13. Modulation of luminescence operon expression by N-octanoyl-L-homoserine lactone in ainS mutants of Vibrio fischeri.  |  Kuo, A., et al. 1996. J Bacteriol. 178: 971-6. PMID: 8576070

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-octanoyl-L-Homoserine lactone, 5 mg

sc-222011
5 mg
$77.00

N-octanoyl-L-Homoserine lactone, 10 mg

sc-222011A
10 mg
$102.00

N-octanoyl-L-Homoserine lactone, 25 mg

sc-222011B
25 mg
$224.00

N-octanoyl-L-Homoserine lactone, 50 mg

sc-222011C
50 mg
$388.00