Date published: 2026-5-2

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N-Octanoyl-β-D-glucosylamine (CAS 134403-86-4)

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CAS Number:
134403-86-4
Molecular Weight:
305.37
Molecular Formula:
C14H27NO6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Octanoyl-β-D-glucosylamine is a synthetic glycolipid that combines a fatty acid (octanoic acid) with a glucose-derived amine through an amide linkage, forming a molecule with distinctive amphiphilic properties — possessing both hydrophilic and hydrophobic characteristics. This structural arrangement makes it particularly useful in research contexts where mimicking or disrupting biological membranes is necessary. The molecule′s mechanism of action revolves around its ability to integrate into lipid bilayers or to form micelles, depending on its concentration in aqueous solutions. In biochemical research, N-Octanoyl-β-D-glucosylamine is employed to study the role of glycolipids in cellular processes, such as cell signaling and membrane dynamics. Its incorporation into synthetic membranes can alter the physical properties of these bilayers, such as fluidity and phase behavior, thereby providing insights into the fundamental roles of glycolipids in membrane structure and function. In addition, this compound is used in the development of glycolipid-enriched vesicles and liposomes, which serve as models for studying drug delivery systems, helping researchers to understand how drugs can be encapsulated and released from such carriers. N-Octanoyl-β-D-glucosylamine′s unique properties make it a valuable tool for exploring the interactions between lipids and carbohydrates in a controlled environment, offering profound insights into biomembrane mimicry and interaction without direct therapeutic implications.


N-Octanoyl-β-D-glucosylamine (CAS 134403-86-4) References

  1. Baculoviral expression of an integral membrane protein for structural studies.  |  Madden, DR. and Safferling, M. 2007. Methods Mol Biol. 363: 39-57. PMID: 17272836
  2. Impact of the chemical structure on amphiphilic properties of sugar-based surfactants: A literature overview.  |  Gaudin, T., et al. 2019. Adv Colloid Interface Sci. 270: 87-100. PMID: 31200263
  3. Synthesis and characterization of N-octanoyl-beta-D-glucosylamine, a new surfactant for membrane studies.  |  Brenner-Hénaff, C., et al. 1993. Anal Biochem. 212: 117-27. PMID: 8368483
  4. An efficient acylation of free glycosylamines for the synthesis of N-glycosyl amino acids and N-glycosidic surfactants for membrane studies  |  Plusquellec, D., Brenner-Hénaff, C., Léon-Ruaud, P., Duquenoy, S., Lefeuvre, M., & Wróblewski, H. 1994. Journal of carbohydrate chemistry. 13(5): 737-751.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Octanoyl-β-D-glucosylamine, 500 mg

sc-281086
500 mg
$200.00