Date published: 2026-4-5

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N,N′-Dimethylthiourea (CAS 534-13-4)

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CAS Number:
534-13-4
Purity:
≥98%
Molecular Weight:
104.17
Molecular Formula:
C3H8N2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N,N′-Dimethylthiourea (DMTU), a white crystalline solid with a slight odor, is an organic compound that exhibits solubility in water. N,N′-Dimethylthiourea serves as a vital reagent in synthesizing a range of compounds, including peptides and thiol-containing compounds. It also acts as a catalyst for polymer synthesis and contributes to the production of fine chemicals. Additionally, N,N′-Dimethylthiourea finds application as a reagent in synthesizing both organic and inorganic compounds. Although the exact mechanism of action of N,N′-Dimethylthiourea remains incompletely understood, it is believed to function as a chelating agent. By binding to metal ions and forming complexes, it facilitates reactions with other molecules, leading to the formation of diverse compounds.


N,N′-Dimethylthiourea (CAS 534-13-4) References

  1. Role of chelate substituents and cis sigma-effect on the rate of ligand substitution at Pt(N-N-N) and Pt(N-N-C) centres.  |  Jaganyi, D., et al. 2004. Dalton Trans. 299-304. PMID: 15356727
  2. Protective effect of N,N'-dimethylthiourea against stress-induced gastric mucosal lesions in rats.  |  Ohta, Y., et al. 2017. Fundam Clin Pharmacol. 31: 319-328. PMID: 28107553
  3. N,N'-dimethylthiourea dioxide formation from N,N'-dimethylthiourea reflects hydrogen peroxide concentrations in simple biological systems.  |  Curtis, WE., et al. 1988. Proc Natl Acad Sci U S A. 85: 3422-5. PMID: 3130627
  4. Infrared absorption spectra of metal complexes of alkylthioureas and some related ligands  |  Gosavi, R. K., & Rao, C. N. R. 1967. Journal of Inorganic and Nuclear Chemistry. 29(8): 1937-1945.
  5. The thermochemistry of complexes of N-substituted thioureas with cobalt (II) and nickel (II) chlorides  |  Ashcroft, S. J. 1971. The Journal of Chemical Thermodynamics. 3(6): 853-859.
  6. Some substituted thiourea complexes of molybdenum carbonyl  |  Baghlaf, A. O., Ishaq, M., & Daifuliah, A. S. 1984. Polyhedron. 3(2): 235-238.
  7. Multinuclear NMR (1H, 13C, 15N and 107Ag) studies of the silver cyanide complexes of thiourea and substituted thioureas  |  Ahmad, S., Isab, A. A., & Ashraf, W. 2002. Inorganic Chemistry Communications. 5(10): 816-819.
  8. A distinguishing of adsorption–catalyzed and regular part of faradaic current for inorganic cation–organic adsorbate system: probabilistic curves in cyclic voltammetry and normal pulse polarography  |  Sanecki, P. 2004. Electrochemistry communications. 6(8): 753-756.
  9. Adsorption of N, N′-dimethylthiourea at a mercury/aqueous solution of NaClO4 interface; dependence on the supporting electrolyte concentration  |  Nosal-Wiercińska, A., & Dalmata, G. 2006. Electrochimica acta. 51(27): 6179-6185.
  10. Mercury (II) cyanide complexes of thioureas and the crystal structure of [(N-methylthiourea) 2 Hg (CN) 2]  |  Isab, A. A., Fettouhi, M., Malik, M. R., Ali, S., Fazal, A., & Ahmad, S. 2011. Russian Journal of Coordination Chemistry. 37: 180-185.
  11. Facile synthesis and crystal structure of 1, 5-dimethyl-6-thioxo-1, 3, 5-triazinane-2, 4-dione  |  Shajari, N., Kazemizadeh, A. R., Ramazani, A., Joo, S. W., Ślepokura, K., Lis, T., & Souldozi, A. 2015. Journal of Structural Chemistry. 56: 806-810.
  12. DNA binding, topoisomerase inhibition and cytotoxicity of palladium (II) complexes with 1, 10-phenanthroline and thioureas  |  Barra, C. V., Rocha, F. V., Morel, L., Gautier, A., Garrido, S. S., Mauro, A. E.,.. & Netto, A. V. 2016. Inorganica Chimica Acta. 446: 54-60.
  13. Synthesis, X-ray structures and antibacterial activities of silver (I) complexes of 1, 3-bis (diphenylphosphano) propane (Dppp) and N, N′-dimethylthiourea (Dmtu)  |  Ahmad, S., Choudhary, M. A., Tahir, M. N., Ali, I., Aslam, M., Fettouhi, M.,.. & Alharthi, A. I. 2020. Polyhedron. 175: 114209.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N,N′-Dimethylthiourea, 5 g

sc-250537
5 g
$38.00

N,N′-Dimethylthiourea, 100 g

sc-250537A
100 g
$89.00