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N-Nitrosohexamethyleneimine (CAS 932-83-2)

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Alternate Names:
Hexahydro-1-nitrosoazepine
CAS Number:
932-83-2
Molecular Weight:
128.17
Molecular Formula:
C6H12N2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Nitrosohexamethyleneimine is frequently studied in the field of chemical synthesis and environmental science. Researchers investigate its role in the formation of nitrosamines, a class of compounds known for their occurrence in various industrial and natural processes. Studies on N-Nitrosohexamethyleneimine focus on its chemical behavior under different environmental conditions, such as its stability and degradation pathways. This research is essential for understanding how N-Nitrosohexamethyleneimine and similar compounds might impact environmental health. Additionally, N-Nitrosohexamethyleneimine is used in the synthesis of other chemicals, where its reactivity and transformation into different compounds are explored to optimize production processes and reduce potential environmental and health risks.


N-Nitrosohexamethyleneimine (CAS 932-83-2) References

  1. Attempt to adsorb N-nitrosamines in solution by use of zeolites.  |  Zhu, JH., et al. 2001. Chemosphere. 44: 949-56. PMID: 11513428
  2. Free radical chemistry of advanced oxidation process removal of nitrosamines in water.  |  Landsman, NA., et al. 2007. Environ Sci Technol. 41: 5818-23. PMID: 17874792
  3. Hierarchical Composites to Reduce N-Nitrosamines in Cigarette Smoke.  |  Li, YY., et al. 2015. Materials (Basel). 8: 1325-1340. PMID: 28788003
  4. Strain comparison of systemic N-nitrosohexamethyleneimine carcinogenesis in BALB/c, SENCAR and CD-1 mice.  |  Strickland, PT., et al. 1988. Cancer Lett. 41: 139-46. PMID: 3401840
  5. In Silico Drug Screening Analysis against the Overexpression of PGAM1 Gene in Different Cancer Treatments.  |  Fareed, MM., et al. 2021. Biomed Res Int. 2021: 5515692. PMID: 34195264
  6. Monitoring a potential carcinogen in pharmaceutical formulations at the low part per billion level. High-performance liquid chromatographic determination of N-nitrosohexamethyleneimine in tolazamide.  |  Severin, G. 1987. J Chromatogr. 386: 57-63. PMID: 3558617
  7. Phosphoglycerate mutase 1 that is essential for glycolysis may act as a novel metabolic target for predicating poor prognosis for patients with gastric cancer.  |  Wei, C., et al. 2022. J Clin Lab Anal. 36: e24718. PMID: 36181311
  8. Metabolism and mutagenicity of N-nitrosohexamethyleneimine and its hydroxylated derivatives.  |  Hecker, LI., et al. 1983. Teratog Carcinog Mutagen. 3: 9-17. PMID: 6132461
  9. In vivo binding of N-nitrosopyrrolidine and N-nitrosohexamethyleneimine to non-purine sites on rat liver DNA.  |  Ross, AE. and Lawson, TA. 1982. Cancer Lett. 15: 329-34. PMID: 6180827
  10. Carcinogenesis by N-nitrosohexamethyleneimine in NZO inbred mice.  |  Goodall, CM. and Lijinsky, W. 1984. Toxicology. 33: 251-9. PMID: 6515660
  11. Strain and sex differences in N-nitrosohexamethyleneimine carcinogenesis in NZB, NZC, NZO, and NZY mice.  |  Goodall, CM. and Lijinsky, W. 1984. J Natl Cancer Inst. 73: 1215-8. PMID: 6593491
  12. Formation of epsilon-hydroxycaproate and epsilon-aminocaproate from N-nitrosohexamethyleneimine: evidence that microsomal alpha-hydroxylation of cyclic nitrosamines may not always involve the insertion of molecular oxygen into the substrate.  |  Hecker, LI., et al. 1984. Chem Biol Interact. 49: 235-48. PMID: 6722936
  13. Comparison of the in vitro metabolism of N-nitrosohexamethyleneimine by rat liver and lung microsomal fractions.  |  Hecker, LI. and McClusky, GA. 1982. Cancer Res. 42: 59-64. PMID: 7053868

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Nitrosohexamethyleneimine, 1 g

sc-215472
1 g
$99.00

N-Nitrosohexamethyleneimine, 5 g

sc-215472A
5 g
$421.00