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N-Nitrosodiphenylamine (CAS 86-30-6)

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Alternate Names:
Diphenylnitrosamine; Diphenylnitrosoamine; N-Nitroso-N-phenylaniline
CAS Number:
86-30-6
Purity:
≥97%
Molecular Weight:
198.22
Molecular Formula:
C12H10N2O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Nitrosodiphenylamine, an industrial compound. This orange-brown or yellow solid finds its use in the manufacturing of rubber products, such as tires, as well as in the production of various chemicals. The occurrence of N-nitrosodiphenylamine in the natural environment remains uncertain. However, there is some evidence suggesting that microorganisms may play a role in its production. As for its physical properties, N-nitrosodiphenylamine exists as a yellow to brown or orange powder, flakes, or a black solid. It is insoluble in water and possesses a greater density than water, causing it to sink when in contact with it. It is worth noting that N-nitrosodiphenylamine belongs to the phenylhydrazines group of compounds.


N-Nitrosodiphenylamine (CAS 86-30-6) References

  1. Bioassay of N-nitrosodiphenylamine for possible carcinogenicity.  |  ,. 1979. Natl Cancer Inst Carcinog Tech Rep Ser. 164: 1-123. PMID: 12799698
  2. Oxidation of 1,1-diphenylhydrazine to N-nitrosodiphenylamine by superoxide radical in the eye.  |  Nikaido, H., et al. 1992. Jpn J Ophthalmol. 36: 103-7. PMID: 1321925
  3. Formation of N-nitrosodiphenylamine and two new N-containing disinfection byproducts from chloramination of water containing diphenylamine.  |  Zhou, WJ., et al. 2009. Environ Sci Technol. 43: 8443-8. PMID: 19924982
  4. Subchronic urinary bladder toxicity evaluation of N-Nitrosodiphenylamine in Fischer 344 rats.  |  Dodd, DE., et al. 2013. J Appl Toxicol. 33: 383-9. PMID: 22893110
  5. Pharmacokinetics of biliary excretion of N-nitrosodiphenylamine (NDPA) in animals of different species.  |  Atawodi, SE. and Maduagwu, EN. 1990. Eur J Drug Metab Pharmacokinet. 15: 27-9. PMID: 2384114
  6. Development of mutagenicity during degradation of N-nitrosamines by advanced oxidation processes.  |  Mestankova, H., et al. 2014. Water Res. 66: 399-410. PMID: 25240607
  7. Occurrence of N-nitrosamines in U.S. freshwater sediments near wastewater treatment plants.  |  Gushgari, AJ., et al. 2017. J Hazard Mater. 323: 109-115. PMID: 27067539
  8. Molecularly imprinted solid phase extraction coupled with gas chromatography-mass spectrometry for determination of N-Nitrosodiphenylamine in water samples.  |  Li, Z., et al. 2018. Chemosphere. 212: 872-880. PMID: 30195167
  9. Mutagenic activity and specificity of N-nitrosomethylaniline and N-nitrosodiphenylamine in Salmonella.  |  Zielenska, M. and Guttenplan, JB. 1988. Mutat Res. 202: 269-76. PMID: 3054528
  10. [Determination of N-nitrosodiphenylamine in meat canned food for children by the method of chromato-massspectrometry].  |  Zaytseva, NV., et al. 2017. Vopr Pitan. 86: 56-62. PMID: 30695629
  11. Reductive metabolism of N-nitrosodiphenylamine to the corresponding hydrazine derivative.  |  Tatsumi, K., et al. 1983. Arch Biochem Biophys. 226: 174-81. PMID: 6639050
  12. N-Nitrosodiphenylamine.  |  . 1982. IARC Monogr Eval Carcinog Risk Chem Hum. 27: 213-25. PMID: 7049904
  13. Occupational exposure to N-nitroso compounds.  |  Rappe, C. and Rydström, T. 1980. IARC Sci Publ. 565-74. PMID: 7228280
  14. The genetic toxicology of N-nitrosodiphenylamine.  |  McGregor, D. 1994. Mutat Res. 317: 195-211. PMID: 7515154

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Nitrosodiphenylamine, 1 g

sc-257863
1 g
$82.00