Molecular structure of N-Nitrosodiisopropylamine, CAS Number: 601-77-4
N-Nitrosodiisopropylamine (CAS 601-77-4)
Alternate Names:
N-(1-Methylethyl)-N-nitroso-2-propanamine; 1,1′-Dimethyl-N-nitrosodiethylamine
Application:
N-Nitrosodiisopropylamine is a nitroso compound that shows carcinogenic effects.
CAS Number:
601-77-4
Molecular Weight:
130.19
Molecular Formula:
C6H14N2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
N-Nitrosodiisopropylamine (NDIPA) is an organic compound widely used in the synthesis of nitro compounds, such as nitroaromatic compounds, nitroalkanes, and nitramines. It reacts with nitric oxide to form nitrosamines, which are known to be carcinogenic and cause cellular damage. It is also used as a reagent for the detection of free radicals. It may act to inhibit the activity of nitric oxide synthase, cyclooxygenase, and superoxide dismutase. Researchers utilize NDIPA to study the role and effects of nitric oxide on the cardiovascular system, nervous system, inflammation, oxidative stress, and the development and progression of cancer.
N-Nitrosodiisopropylamine (CAS 601-77-4) References
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- Comparison of EI-GC-MS/MS, APCI-LC-MS/MS, and ESI-LC-MS/MS for the Simultaneous Analysis of Nine Nitrosamines Eluted from Synthetic Resins into Artificial Saliva and Health Risk Assessment. | Kim, H., et al. 2021. Toxics. 9: PMID: 34678926
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- A substructure-based screening approach to uncover N-nitrosamines in drug substances. | Kao, YT., et al. 2022. J Food Drug Anal. 30: 150-162. PMID: 35647726
- A multi-analyte LC-MS/MS method for screening and quantification of nitrosamines in sartans. | Chang, SH., et al. 2020. J Food Drug Anal. 28: 292-301. PMID: 35696119
- Collaborative reliance in medicine safety and quality regulation: Investigation of experiences in handling N-nitrosamine impurities among ZaZiBoNa participating countries. | Shabangu, PP., et al. 2022. Front Med (Lausanne). 9: 975032. PMID: 36160156
- Determination of Genotoxic Impurity N-Nitroso-N-methyl-4-aminobutyric Acid in Four Sartan Substances through Using Liquid Chromatography-Tandem Mass Spectrometry. | Xie, B., et al. 2022. Molecules. 27: PMID: 36364326
- Risk assessment of N-nitrosamines in food. | , ., et al. 2023. EFSA J. 21: e07884. PMID: 36999063
- Photochemistry of N-nitrosamines in neutral media. | Michejda, CJ. and Rydstrom, T. 1984. IARC Sci Publ. 365-9. PMID: 6533027
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Nitrosodiisopropylamine, 10 mg | sc-212261 | 10 mg | $338.00 | |||
N-Nitrosodiisopropylamine, 25 mg | sc-212261A | 25 mg | $714.00 |