N-Nitrosodiisobutylamine (CAS 997-95-5)
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N-Nitrosodiisobutylamine functions as a direct-acting alkylating agent, forming covalent adducts with nucleophilic groups on DNA, RNA, and proteins. It induces DNA damage by alkylating DNA bases, leading to the formation of DNA adducts and cross-links. N-Nitrosodiisobutylamine has the ability to disrupt DNA replication and transcription processes, ultimately causing mutations and cell death. N-Nitrosodiisobutylamine′s mechanism of action involves the activation of cellular signaling pathways related to DNA damage and repair, leading to the activation of cell cycle checkpoints and apoptosis. It may induce oxidative stress and the generation of reactive oxygen species, contributing to its genotoxic effects. N-Nitrosodiisobutylamine′s mechanism of action involves its ability to directly interact with cellular macromolecules, leading to genetic and cellular damage.
N-Nitrosodiisobutylamine (CAS 997-95-5) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Nitrosodiisobutylamine, 50 mg | sc-460301 | 50 mg | $290.00 | |||
N-Nitrosodiisobutylamine, 100 mg | sc-460301A | 100 mg | $583.00 |