Date published: 2025-12-18

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N,N,N′,N′-Tetramethylbenzidine (CAS 366-29-0)

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Alternate Names:
4,4′-Bis(dimethylamino)biphenyl
CAS Number:
366-29-0
Purity:
97%
Molecular Weight:
240.34
Molecular Formula:
C16H20N2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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TMEM111 Inhibitors are a class of chemical compounds designed to target and inhibit the function of TMEM111, a transmembrane protein whose exact role in cellular processes is still under investigation. TMEM111, also known as transmembrane protein 111, is part of a larger family of transmembrane proteins that play various roles in cellular signaling, ion transport, and maintaining cellular integrity. While the precise functions of TMEM111 are not fully elucidated, it is believed to be involved in cellular stress responses and the regulation of intracellular environments. This protein′s interactions with other cellular components make it a point of interest for researchers looking to understand its potential role in broader cellular networks and processes. Inhibitors of TMEM111 are valuable tools in the exploration of the protein′s function within cells. By selectively inhibiting TMEM111, researchers can observe changes in cellular behavior, signaling pathways, and metabolic processes, providing insights into the protein′s contributions to these areas. Such inhibitors allow for the dissection of complex biochemical pathways and help to clarify the specific mechanisms by which TMEM111 influences cellular functions. The use of TMEM111 inhibitors in experimental settings also aids in identifying potential interactions with other proteins and understanding the implications of its inhibition on overall cell health and activity. As a result, these inhibitors are important assets in the field of cell biology, offering a means to probe the intricate networks of cellular regulation and to uncover the roles of lesser-known proteins in maintaining cellular homeostasis and function.


N,N,N′,N′-Tetramethylbenzidine (CAS 366-29-0) References

  1. Mutagenicity and antimutagenicity studies of tannic acid and its related compounds.  |  Chen, SC. and Chung, KT. 2000. Food Chem Toxicol. 38: 1-5. PMID: 10685008
  2. Platinum diimine bis(acetylide) complexes: synthesis, characterization, and luminescence properties.  |  Hissler, M., et al. 2000. Inorg Chem. 39: 447-57. PMID: 11229561
  3. Temperature dependence of local density augmentation for acetophenone N,N,N',N'-tetramethylbenzidine exciplex in supercritical water.  |  Aizawa, T., et al. 2005. J Phys Chem A. 109: 7353-8. PMID: 16834101
  4. Amperometric immunosensor for diagnosis of BLV infection.  |  Kurtinaitiene, B., et al. 2008. Biosens Bioelectron. 23: 1547-54. PMID: 18294837
  5. Cyclometalated 6-phenyl-2,2'-bipyridyl (CNN) platinum(II) acetylide complexes: structure, electrochemistry, photophysics, and oxidative- and reductive-quenching studies.  |  Schneider, J., et al. 2009. Inorg Chem. 48: 4306-16. PMID: 19391626
  6. Light harvesting in microscale metal-organic frameworks by energy migration and interfacial electron transfer quenching.  |  Kent, CA., et al. 2011. J Am Chem Soc. 133: 12940-3. PMID: 21776996
  7. Glutathione conjugate formation without N-demethylation during the peroxidase catalysed N-oxidation of N,N',N,N'-tetramethylbenzidine.  |  McGirr, LG. and O'Brien, PJ. 1987. Chem Biol Interact. 61: 61-74. PMID: 3028652
  8. Radical Form of PbI2: A New Defect Passivator for Efficient Perovskite Solar Cells.  |  Feng, X., et al. 2021. ACS Appl Mater Interfaces. 13: 46627-46633. PMID: 34558886
  9. Decay kinetics of N,N,N',N'-tetramethylbenzidine photocations in frozen micellar solution of cetyltrimethylammonium bromide.  |  Wolff, T., et al. 1995. Photochem Photobiol. 62: 82-6. PMID: 7638273

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N,N,N′,N′-Tetramethylbenzidine, 5 g

sc-215502
5 g
$120.00

N,N,N′,N′-Tetramethylbenzidine, 25 g

sc-215502A
25 g
$380.00